On 1 September 2012, HSMC celebrates 40 years! As is often the case, such a birthday is an opportunity to look back at our past, but also to take stock of where the NHS is now and what the future may hold – particularly in a difficult policy and financial context. We will be celebrating throughout the year in various ways, so please keep in touch with us via www.hsmc.bham.ac.uk. However, two of...

Patients with bilateral hippocampal damage acquired in adulthood who are amnesic for past events have also been reported to be impaired at imagining fictitious and future experiences. One such patient, P01, however, was found to be unimpaired on these tasks despite dense amnesia and 50% volume loss in both hippocampi. P01 might be an atypical case, and in order to investigate this we identified...

Jon P. Furuno, James H. Maguire, Heather P. Green, Judith A. Johnson, Robert Heimer, Stephanie P. Johnston, Christopher R. Braden, Stephen C. Edberg, Susan Bell, and Jon Mark Hirshon Departments of Epidemiology and Preventive Medicine and Emergency Medicine, University of Maryland School of Medicine, Maryland Veterans Affairs Health Care System, Baltimore, Maryland; Department of Epidemiology a...

‘The crucified people’ became a key theological concern in the writings of Jon Sobrino SJ 1990s. This article examines how and why made this central element his theology at time. Section 2 discusses what has described as ‘awakening from sleep inhumanity’ 1970s he encountered liberation El Salvador following doctoral studies Frankfurt. 3 three figures Salvadoran Church who influenced Sobrino: Ig...

Bayesian networks are normally given one of two types of foundations: they are either treated purely formally as an abstract way of representing probability functions , or they are interpreted, with some causal interpretation given to the graph in a network and some standard interpretation of probability given to the probabilities specified in the network. In this chapter I argue that current f...

13 Weinstein, I. B., A. N. Schechter, E. R. Burka, and P. A. Marks, Science, 140, 314 (1963); Gierer, A. J., J. Mol. Biol., 6, 148 (1963). 14 Ochoa, M., Jr., and I. B. Weinstein, J. Biol. Chem., in press. 15 Crick, F. H. C., in Biological Replication of Macromolecules, Symposia of the Society for Experimental Biology (New York: Academic Press, 1958), vol. 12, p. 138. 16 Felsenfeld, G., in Molec...

In pursuing quantitative histochemical investigations aimed at demonstrating the biochemical architecture of human frontal cortex (l-4), we found it necessary to determine ganglioside sialic acid in submicrogram amounts. Even when adapted to the microscale, spectrophotometric methods lack the sensitivity required for studying nervous tissue samples containing less than 0.3 pg of sialic acid. Si...