Este estudo teve como objetivo analisar as ações de enfrentamento à violência contra mulheres realizadas pela equipe multiprofissional da Secretaria Mulher Garanhuns (SecMul) e pelo Centro Especializado Atendimento mulher em situação – Joana Beatriz Lima Silva (CEAM-JB). Trata-se uma pesquisa que parte perspectiva construcionista do conhecimento das epistemologias feministas. A partir dos resul...

BACKGROUND Jolkinolide A (JA) and Jolkinolide B (JB) are diterpenoids extracted from the roots of Euphorbia fischeriana Steud and have been shown to have anti-tumor activity. However, their effects on the ability of tumor cells to invade blood vessels and metastasize remain largely unknown. Investigations into the effects of JA and JB on the angiogenesis of tumor tissues may facilitate the iden...

A20 (also known as TNFAIP3) is a deubiquitinating enzyme (DUB) that ensures optimal immune responses in cells stimulated by cytokines, such as TNF and IL-1, or pathogen components, such as lipopolysaccharide. Deletion of A20 in mice results in multi-organ inflammation and death within 2 weeks [1]. The anti-inflammatory functions of A20 have been attributed to its ability to negatively regulate ...

In the present study, we induced melanomas in C57BL/6 mice by a single application of 7,12-dimethylbenz(a)anthracene to the scapular region of 4-day-old mice, followed by twice-weekly applications of croton oil. Of 20 mice treated, melanomas arose in two female littermates. The first melanoma (JB/MS) arose 16 weeks after initiation of treatment, and the second melanoma (JB/RH) arose 23 weeks la...

In 1976, Kaplansky introduced the class JB∗-algebras which includes all C∗-algebras as a proper subclass. The notion of topological stable rank 1 for C∗-algebras was originally introduced by M. A. Rieffel and was extensively studied by various authors. In this paper, we extend this notion to general JB∗-algebras. We show that the complex spin factors are of tsr 1 providing an example of special...

The network of NF-jB-dependent transcription that activates both proand anti-inflammatory genes in mammals is still unclear. As NF-jB factors are evolutionarily conserved, we used Drosophila to understand this network. The NF-jB transcription factor Relish activates effector gene expression following Gram-negative bacterial immune challenge. Here, we show, using a genome-wide approach, that the...