The pharmacokinetics of alprazolam (ALP) after i.v. and p.o. administration in rats were characterized. ALP decayed biexponentially after the i.v. dose (1.25 mg/kg), but the concentration-time profiles after the p.o. doses (7 and 12.5 mg/kg) exhibited a doublepeak phenomenon. The presence of two peaks was confirmed by statistical analysis of the serum concentration data of ALP, as well as by ob...

The pharmacokinetics of alprazolam (ALP) after i.v. and p.o. administration in rats were characterized. ALP decayed biexponentially after the i.v. dose (1.25 mg/kg), but the concentration-time profiles after the p.o. doses (7 and 12.5 mg/kg) exhibited a doublepeak phenomenon. The presence of two peaks was confirmed by statistical analysis of the serum concentration data of ALP, as well as by ob...

Abee T, Van Schaik W, Siezen RJ. 2004. Impact of genomics on microbial food safety (Review). Trends Biotechnol 22: (12) 653. Alaoui-Jamali MA, Dupre I, Qiang H. 2004. Prediction of drug sensitivity and drug resistance in cancer by transcriptional and proteomic profiling (Review). Drug Dev Res 7: (4-5) 245. Aldred S, Grant MM, Griffiths HR. 2004. The use of proteomics for the assessment of clini...

The pharmacokinetics of alprazolam (ALP) after i.v. and p.o. administration in rats were characterized. ALP decayed biexponentially after the i.v. dose (1.25 mg/kg), but the concentration-time profiles after the p.o. doses (7 and 12.5 mg/kg) exhibited a doublepeak phenomenon. The presence of two peaks was confirmed by statistical analysis of the serum concentration data of ALP, as well as by ob...

Research in software architecture has emphasized compositional development, where the computational aspects of a system are modularly separated from communication and coordination aspects. Typically, software architectures are factored into a set of components, which encapsulate computation, and connectors, which encapsulate interactions. In terms of design, development and debugging, this sepa...

The pharmacokinetics of alprazolam (ALP) after i.v. and p.o. administration in rats were characterized. ALP decayed biexponentially after the i.v. dose (1.25 mg/kg), but the concentration-time profiles after the p.o. doses (7 and 12.5 mg/kg) exhibited a doublepeak phenomenon. The presence of two peaks was confirmed by statistical analysis of the serum concentration data of ALP, as well as by ob...

Research in software architecture has emphasized compositional development, where the computational aspects of a system are modularly separated from communication and coordination aspects. Typically, software architectures are factored into a set of components, which encapsulate computation, and connectors, which encapsulate interactions. In terms of design, development and debugging, this sepa...

The pharmacokinetics of alprazolam (ALP) after i.v. and p.o. administration in rats were characterized. ALP decayed biexponentially after the i.v. dose (1.25 mg/kg), but the concentration-time profiles after the p.o. doses (7 and 12.5 mg/kg) exhibited a doublepeak phenomenon. The presence of two peaks was confirmed by statistical analysis of the serum concentration data of ALP, as well as by ob...

The pharmacokinetics of alprazolam (ALP) after i.v. and p.o. administration in rats were characterized. ALP decayed biexponentially after the i.v. dose (1.25 mg/kg), but the concentration-time profiles after the p.o. doses (7 and 12.5 mg/kg) exhibited a doublepeak phenomenon. The presence of two peaks was confirmed by statistical analysis of the serum concentration data of ALP, as well as by ob...

Following a previous BEER editorial on responsible business engagement with sustainability and the United Nations' 17 Sustainable Development Goals (SDGs) (Jamali et al., 2022), in this we intend to shed light tackling problems via organizational openness.1 In general, (e.g., poverty, irresponsible production consumption, planet harming) are broad scope have several interrelated facets (Gurca 2...