In this paper a special complex Kn of abstract cubes [2, 3], which contains only n-dimensional cubes is examined. The border of this complex is an abstract (n − 1)-dimensional sphere. It is proved that the abstract sphere contains at least one 0dimensional cube, which belongs to exactly n cubes with dimension 1, if the complex is a homogeneous n-dimensional tree. This result allows to solve, in...

Enzymes, as biological catalysts, form the basis of all forms of life. How these proteins have evolved their functions remains a fundamental question in biology. Over 100 years of detailed biochemistry studies, combined with the large volumes of sequence and protein structural data now available, means that we are able to perform large-scale analyses to address this question. Using a range of c...

This paper presents a novel featurebased semantic role labeling (SRL) method which uses both constituent and dependency syntactic views. Comparing to the traditional SRL method relying on only one syntactic view, the method has a much richer set of syntactic features. First we select several important constituent-based and dependency-based features from existing studies as basic features. Then,...

Preparata and Vuillemin proposed the cube-connected cycles (CCC) in 1981 16], and in the same paper, gave an asymptotically-optimal layout scheme for the CCC. We give a new layout scheme for the CCC which requires less than half of the area of the Preparata-Vuillemin layout. We also give a non-trivial lower bound on the layout area of the CCC. There is a constant factor of 2 between the new lay...

Glucuronidation mediated by uridine 5'-diphospho (UDP)-glucuronosyltransferase is an important detoxification pathway. However, identifying a selective probe of UDP- glucuronosyltransferase is complicated because of the significant overlapping substrate specificity displayed by the enzyme. In this paper, desacetylcinobufagin (DACB) 3-O- and 16-O-glucuronidation were found to be isoform-specific...

The induced matching partition number of a graph G, denoted by imp(G), is the minimum integer k such that V(G) has a k-partition (V1, V2 ... Vk ) such that, for each i, 1 ≤ i ≤ k, G[Vi], the subgraph of G induced by Vi, is a 1-regular graph. The induced matching k-partition problem is NP-complete even for k = 2. In this paper we investigate the induced matching partition problem for butterfly n...

OBJECTIVES To investigate the effect of three cycling cadences on a subsequent 3000 m track running performance in well trained triathletes. METHODS Nine triathletes completed a maximal cycling test, three cycle-run succession sessions (20 minutes of cycling + a 3000 m run) in random order, and one isolated run (3000 m). During the cycling bout of the cycle-run sessions, subjects had to maint...

Bistability, and more generally multistability, is a key system dynamics feature enabling decision-making and memory in cells. Deciphering the molecular determinants of multistability is thus crucial for a better understanding of cellular pathways and their (re)engineering in synthetic biology. Here, we show that a key motif found predominantly in eukaryotic signalling systems, namely a futile ...

We show that an artin algebra Λ having at most three radical layers of infinite projective dimension has finite finitistic dimension, generalizing the known result for algebras with vanishing radical cube. We also give an equivalence between the finiteness of fin.dim.Λ and the finiteness of a given class of Λ-modules of infinite projective dimension.

In the August issue of TiPS, Epand and Lester analysed the effect of the physicochemical properties of the membrane on protein kinase C activity. In addition to those substrates discussed that require the presence of Ca2+ and phospholipids, other substrates can be phosphorylated in the absence of these activators. It is possible that this differential substrate requirement could be exploited ph...