Diabetic retinopathy is accompanied by disturbances in retinal blood flow, which is assumed to be related to the diabetic metabolic dysregulation. It has previously been shown that normoinsulinemic hyperglycemia has no effect on the diameter of retinal arterioles at rest and during an increase in the arterial blood pressure induced by isometric exercise. However, the influence of hyperinsulinem...

BACKGROUND No study relating the changes obtained in the architecture of erector spinae (ES) muscle were registered with ultrasound and different intensities of muscle contraction recorded by surface EMG (electromyography) on the ES muscle was found. The aim of this study was analyse the relationship in the response of the ES muscle during isometric moderate and light lumbar isometric extension...

The neural substrates of fatigue induced by muscular activity have been addressed in depth in relation to isometric tasks. For these activities, when fatigue develops, it has been noted that the duration of the silent periods (SPs) increases in response to both transcranial magnetic stimulation (TMS) of primary motor cortex or electric cervicomedullary stimulation (CMS). However, fatigue is kno...

We tested the hypothesis that lengthening contractions and subsequent muscle fiber degeneration and/or regeneration are required to induce exercise-associated protection from lengthening contraction-induced muscle injury. Extensor digitorum longus muscles in anesthetized mice were exposed in situ to repeated lengthening contractions, isometric contractions, or passive stretches. Three days afte...

We explored the retraction or contraction of platelet-fibrin clots under isometric conditions. In the presence of micromolar calcium clots of normal platelet-rich plasma developed tension at an initial rate of 0.1 to 0.2 g/min per cm2 (initial cross-sectional area). Electron microscopy of clots fixed after attaining a force of 1.6 g/cm2 revealed platelets with elongated bodies and pseudopods in...

objectives: it is well known that neuromuscular function is temperature sensitive. changing of muscle temperature can effect voluntary muscle contraction. the aim of this study was to investigate the effects of cooling and heating on maximal isometric force generated by the elbow flexor musculature in male subjects. methods: forty five healthy males encompassing 3 groups participated in the cur...

* Correspondence to: Vida Garalienė, Intitute of Cardiology Kaunas University of Medicine, Sukilėlių 17, LT-50009 Kaunas, Lithuania. E-mail: [email protected] Studies have shown that 1-acyl-5,6-diethoxy-2-methylthiobenzimidazole derivatives 3-pyridyl(1); 2-pyridyl(2); 4-thiazolyl(3); 4-pyridyl(4); methyl(5); 2-thienyl(6) and 1-acetyl-5,6-dimethoxy-2-methylthiobenzimidazole (7) exhibit po...

relutionshi~ of vascular smooth muscle. Am. J Physiol. 2 2 5 (3) : 664-670. 1973.-Segments of dog carotid artery were excised, cannulated, and restored to in situ length. They were immersed in a KrebsRinger bath and inflated with 100% 02 under nonoscillating pressures. Diameter was continuously monitored with a linear displacement transducer. The vessel segments were relaxed, then treated with ...

The systolic time intervals have been measured in 76 normal children, aged 1 month to 15 years, from simultaneous recordings of the electrocardiogram, phonocardiogram and carotid arterial pulse or apexcardiogram (left or right). Four different statistical methods were applied to study the separate influence of heart rate (HR) and age on these intervals. Left ventricular ejection time (LVET) had...

To investigate the possible role of an alteration in excitation-contraction coupling in cardiac hypertrophy, we compared simultaneously recorded action potentials along with isometric or isotonic contractions of normal and hypertrophied papillary muscles. Hypertrophy was produced by renal hypertension in rats. Hypertrophied papillary muscles were taken from rats that had been hypertensive for 1...