نتایج جستجو برای: isoliquiritigenin
تعداد نتایج: 260 فیلتر نتایج به سال:
Guanjiekang (GJK) that is formed by five medicinal herbs including Astragali Radix, Aconiti Lateralis Radix Praeparaia, Glycyrrhizae Radix et Rhizoma, Corydalis Rhizoma and Paeoniae Radix Alba was used for the treatment of rheumatoid arthritis (RA). However, the pharmacokinetic (PK) profile of active components in GJK remains unclear. This study aims to evaluate the pharmacokinetic behavior of ...
Licorice derived from the roots and rhizomes of Glycyrrhiza uralensis Fisch. (Fabaceae), is one of the most widely-used traditional herbal medicines in China. It has been reported to possess significant analgesic activity for treating spastic pain. The aim of this study is to investigate the spasmolytic molecular mechanism of licorice on oxytocin-induced uterine contractions and predict the rel...
Abstract Skin ischemia-reperfusion (I/R) injury is a serious condition that compromises skin flap surgery and leads to organ dysfunction. It arose due restoration of blood supply after prolonged ischemia. The present study was conducted explore the possible protective Isoliquiritigenin (ISL) on in rats. ISL administered rats dose 10 mg/kg, 20 30 mg/kg. effect quantified tissue following I/R var...
As one of the most promising formulations for poorly water-soluble drugs, nanocrystals have been attracting increasing attention in recent years. Isoliquiritigenin (ISL) is a flavonoid with chalcone structure, and possesses many biological activities. However, its clinical application significantly limited mainly due to low oral bioavailability caused by poor hydrophilicity. To address this, IS...
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