7S anti-IgGs were isolated from four rabbit antistreptococcal antisera by the use of immunoabsorbent columns. The isolated proteins were of restricted molecular heterogeneity; they formed a monodisperse band on microzone electrophoresis and had a limited number of light chain bands when analyzed on urea polyacrylamide gel. The binding site of the 7S anti-IgGs was detected in the F(ab')(2) porti...

Abstract Ganoderma lucidum or Reishi is a medicinal mushroom of significant importance that being used for the prevention and treatment various diseases, due to its numerous pharmacological therapeutic properties. The Ganodermataceae family diverse, but focus on species because specific biologically active macromolecules such as polysaccharides, triterpenoids, steroids, phenolic compounds, lact...

Objective(s): Juglone is isolated from many species of the Juglandaceae family and used as an anti-viral, anti-bacterial, and anti-tumor therapeutic. Here, we evaluated juglone-induced antitumor effect in ovarian cancer SKOV3 cells. Materials and Methods: MTT assay was performed to examine juglone anti-proliferative effect. Cell cycle and apoptosis were studied using flow cytometry in juglone-t...

Abstract In the present study, eleven compounds (1-11) including nine alkaloids (1-9), one triterpenoid saponin (10) and one formamide (11) were isolated from Talaromyces sp. LGT-2, an endophytic fungus from Tripterygium wilfordi. Their structures were determined based on NMR and ESI-MS spectral data, as well as comparing with previous literature data. This is the first report of the isolation ...

Abstract In the present study, eleven compounds (1-11) including nine alkaloids (1-9), one triterpenoid saponin (10) and one formamide (11) were isolated from Talaromyces sp. LGT-2, an endophytic fungus from Tripterygium wilfordi. Their structures were determined based on NMR and ESI-MS spectral data, as well as comparing with previous literature data. This is the first report of the isolation ...

This study was undertaken to characterize pharmacologically the negative chronotropic and antiarrhythmic action of atropine and other tropane analogues. Insight into the site of action of these drugs was obtained by comparing the effects on isolated heart preparations. Dose-response curves were constructed for the negative chronotropic action on the cat Langendorff preparation and refractory pe...

Isolated hepatic tuberculoma is localized hepatic tuberculosis (TB) without bile duct involvement, which presents as solitary or multiple nodular mass lesion of liver mimicking a neoplastic lesion in radiological evaluation. Clinical presentation and biochemical tests for liver functions show non-specific abnormality, which is not helpful for diagnosis. As the treatment, modality of isolated he...

In guinea pig purified antihapten antibodies, the proportion of molecules bearing the kappa- or lambda-type of L chains (K or L molecules) may diverge markedly from that found in normal gamma(2)-globulins. This has been evaluated by precipitation of I(131)-labeled antibody preparations using a specific anti-lambda-chain antiserum. Anti-DNP antibodies isolated 3 wk after immunization of guinea p...