نتایج جستجو برای: ischemic memory

تعداد نتایج: 342412  

Journal: :Evidence-Based Complementary and Alternative Medicine 2012

Journal: :Progress in molecular biology and translational science 2014
Miao-Kun Sun Daniel L Alkon

The protein kinase C (PKC) isoforms, which play an essential role in transmembrane signal conduction, can be viewed as a family of "memory kinases." Evidence is emerging that they are critically involved in memory acquisition and maintenance, in addition to their involvement in other functions of cells. Deficits in PKC signal cascades in neurons are one of the earliest abnormalities in the brai...

Journal: :razavi international journal of medicine 0
shamsi darabi department of physiology and biophysics, faculty of medicine, baqiyatallah university of medical sciences, tehran, iran mohammad taghi mohammadi department of physiology and biophysics, faculty of medicine, baqiyatallah university of medical sciences, tehran, iran; associate professor of physiology, department of physiology and biophysics, faculty of medicine, baqiyatallah university of medical sciences, tehran, iran. tel: ++98-2182483419 zeinab sadat sobhani department of physiology and biophysics, faculty of medicine, baqiyatallah university of medical sciences, tehran, iran

conclusions our findings indicate that fullerenol nanoparticles decrease the brain infarction through enhancement of the sod activity during cerebral ischemia-reperfusion injury. results occlusion of mca induced considerable infarction and lesion in ischemic hemispheres of control ischemic rats (527 ± 59 mm3) in accompany with a decrease in the glutathione content (45%), and sod activity (29%) ...

2012
Kuo-Jen Wu Ming-Tsuen Hsieh Chi-Rei Wu W. Gibson Wood Yuh-Fung Chen

Ischemic stroke results in brain damage and behavioral deficits including memory impairment. Protective effects of green tea extract (GTex) and its major functional polyphenol (-)-epigallocatechin gallate (EGCG) on memory were examined in cerebral ischemic rats. GTex and EGCG were administered 1 hr before middle cerebral artery ligation in rats. GTex, EGCG, and pentoxifylline (PTX) significantl...

2016
Je Hoon Park Sung Eun Kim Jun Jang Jin Han Sung Choi Chang Ju Kim Il Gyu Ko

PURPOSE Perinatal hypoxic-ischemic brain damage is a major cause of acute mortality and chronic neurologic morbidity in infants and children. We investigated the effects of pentoxifylline, a methylxanthine derivative and type-4 phosphodiesterase inhibitor, on short-term memory and apoptotic neuronal cell death in the hippocampus following perinatal hypoxic-ischemia in newborn rats. METHODS We...

Journal: :International journal of geriatric psychiatry 2009
G G Potter D R McQuoid D C Steffens K A Welsh-Bohmer K R R Krishnan

OBJECTIVE The goal of the current study was to examine the neuropsychological profile of magnetic resonance imaging (MRI)-defined subcortical ischemic depression (SID). METHODS Clinically depressed older adults with MRI-defined SID (n = 70) and depressed elders without SID (n = 75) were compared on neuropsychological performance, depression symptoms, and medical burden. RESULTS Group compar...

Jalilvand, Mohammad Reza, Yaghoubi, Ali, FallahMohammadi, Ziya ,

Introduction: Binding of mature brain derived neurotrophic factor (BDNF) to tyrosine kinase B (TrkB) receptor leads to cell survival, while proBDNF binding to p75 receptor leads to cell death. Thus the aim of the present study was to investigate the effects of eight weeks pre-conditioning endurance training on BDNF, TrkB, proBDNF and p75 levels in the hippocampus male rats following ischemic re...

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2007
Satoshi Takeo Norio Takagi Keiko Takagi

Cerebral ischemia causes an irreversible and neurodegenerative disorder that may lead to progressive dementia and global cognitive deterioration. Since the overall process of ischemic brain injuries is extremely complex, treatment with endogenous multifunctional factors would be better choices for preventing complicated ischemic brain injuries. Hepatocyte growth factor, HGF, is a multifunctiona...

2013
Jegan Yogaratnam Rajesh Jacob Sandeep Naik Harish Magadi Kang Sim

Hypoxic-ischemic brain injury encompasses a complex constellation of pathophysiological and cellular brain injury induced by hypoxia, ischemia, cytotoxicity, or combinations of these mechanisms and can result in poor outcomes including significant changes in personality and cognitive impairments in memory, cognition, and attention. We report a case of a male patient with normal premorbid functi...

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