نتایج جستجو برای: ischemic events

تعداد نتایج: 398827  

Journal: :AJNR. American journal of neuroradiology 2007
N Yamada M Higashi R Otsubo T Sakuma N Oyama R Tanaka K Iihara H Naritomi K Minematsu H Naito

BACKGROUND AND PURPOSE To investigate associations between cerebral ischemic events and signal hyperintensity in T1-weighted MR imaging (T1WI) of carotid plaque according to stenosis severity and to estimate persistence of T1WI signal hyperintensity. METHODS A total of 222 patients (392 atherosclerotic carotid arteries) underwent plaque imaging using 3D inversion-recovery-based T1WI (magnetiz...

Journal: :The New England journal of medicine 2011
John H Alexander Renato D Lopes Stefan James Rakhi Kilaru Yaohua He Puneet Mohan Deepak L Bhatt Shaun Goodman Freek W Verheugt Marcus Flather Kurt Huber Danny Liaw Steen E Husted Jose Lopez-Sendon Raffaele De Caterina Petr Jansky Harald Darius Dragos Vinereanu Jan H Cornel Frank Cools Dan Atar Jose Luis Leiva-Pons Matyas Keltai Hisao Ogawa Prem Pais Alexander Parkhomenko Witold Ruzyllo Rafael Diaz Harvey White Mikhail Ruda Margarida Geraldes Jack Lawrence Robert A Harrington Lars Wallentin

BACKGROUND Apixaban, an oral, direct factor Xa inhibitor, may reduce the risk of recurrent ischemic events when added to antiplatelet therapy after an acute coronary syndrome. METHODS We conducted a randomized, double-blind, placebo-controlled clinical trial comparing apixaban, at a dose of 5 mg twice daily, with placebo, in addition to standard antiplatelet therapy, in patients with a recent...

2014
Sorin Giusca Sebastian Kelle Eike Nagel Sebastian Johannes Buss Valentina Puntmann Ernst Wellnhofer Eckart Fleck Hugo Albert Katus Grigorios Korosoglou

AIMS We sought to evaluate the impact of ischemic burden for the prediction of hard cardiac events (cardiac death or nonfatal myocardial infarction) in patients with known or suspected CAD who undergo dobutamine stress cardiac magnetic resonance imaging (DCMR). METHODS We included 3166 patients (pts.), mean age 63 ± 12 years, 27% female, who underwent DCMR in 3 tertiary cardiac centres (Unive...

Journal: :Stroke 2003
Juan F Arenillas José Alvarez-Sabín Carlos A Molina Pilar Chacón Joan Montaner Alex Rovira Bernardo Ibarra Manuel Quintana

BACKGROUND AND PURPOSE The role of inflammation in intracranial large-artery occlusive disease is unclear. We sought to investigate the relationship between high-sensitivity C-reactive protein (CRP) levels and the risk of further ischemic events in first-ever transient ischemic attack (TIA) or stroke patients with intracranial large-artery occlusive disease. METHODS Of a total of 127 consecut...

Journal: :Stroke 2004
Armin J Grau Alexander W Boddy Deborah A Dukovic Florian Buggle Christoph Lichy Tobias Brandt Werner Hacke

BACKGROUND AND PURPOSE Inflammatory markers predict first-time ischemic events. We investigated whether leukocyte and differential counts predict recurrent events and ischemic events in high-risk populations, and whether such events are preceded by acutely exacerbated inflammation. METHODS We studied 18 558 patients with ischemic stroke, myocardial infarction, or peripheral arterial disease w...

Journal: :Stroke 2013
Linxin Li Michela Simoni Wilhelm Küker Ursula G Schulz Sharon Christie Gordon K Wilcock Peter M Rothwell

BACKGROUND AND PURPOSE White matter changes (WMC) are a common finding on brain imaging and are associated with an increased risk of ischemic stroke. They are most frequent in small vessel stroke; however, in the absence of comparisons with normal controls, it is uncertain whether WMC are also more frequent than expected in other stroke subtypes. Therefore, we compared WMC in pathogenic subtype...

2013
Annica Nordin Kerstin Jensen-Urstad Lena Björnådal Susanne Pettersson Anders Larsson Elisabet Svenungsson

INTRODUCTION While microvascular disease is well described in systemic sclerosis (SSc), it is still unclear whether the occurrence of ischemic macrovascular events and atherosclerosis is enhanced among patients with SSc. METHODS In this study, 111 SSc patients (74% of prevalent cases in Stockholm County) and 105 age- and sex-comparable population controls were investigated. Previous ischemic ...

Journal: :Stroke 2013
Dominic P J Howard Guus W van Lammeren Jessica N Redgrave Frans L Moll Jean-Paul P M de Vries Dominique P V de Kleijn Gert Jan de Borst Gerard Pasterkamp Peter M Rothwell

BACKGROUND AND PURPOSE Patients with carotid artery stenosis and ocular ischemic events have a much lower risk of future ipsilateral ischemic stroke on medical treatment and lower procedural risks for endarterectomy and stenting than patients with cerebral ischemic events, and are closer in risk to patients with asymptomatic stenosis. The reasons for this difference in prognosis are not fully u...

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