the use of local anesthesia with lidocaine containing epinephrine in patients with cardiac disease is controversial in the literature. the aim of our study was determining the safety of use the local anesthesia contain epinephrine in patients with ischemic heart disease that undergoing reconstructive surgery. thirty two patients that had known ischemic heart disease and candidate to undergo rec...

objective(s)ischemia-reperfusion injury (iri) is a leading cause of kidney transplantation failure, and ischemic-preconditioning (ipc) is a protective method against the iri. in the present study, the defensive effect of ipc on rats’ kidney was investigated and more importantly the differences between two genders were appraised.materials and methodsthirty two wistar rats were randomly allocated...

background: inflammation and infectious agents such as chlamydia pneumoniae have been associated with cardiovascular disease. objective: to evaluate the serum high sensitivity c - reactive protein (hs-crp) and antibodies against chlamydia pneumoniae and chlamydial heat shock protein-60 (cp-hsp60) in patients with ischemic heart disease (ihd). methods: 62 patients with ihd having either acute my...

To determine the presence of anticardiolipin (aCL) antibodies in patients with ischemic events, we designed a case-control study. We studied 33 patients with unstable angina, 33 male patients with myocardial infarction and 34 control subjects with no evidence of ischemic heart disease. Plasma samples were assessed for IgG anticardiolipin antibodies by enzyme-linked immunosorbent assay (ELI...

background: calcium overload and free radical mediated damage in the mitochondria is the most important pathological changes associated with myocardial ischemic-reperfusion injury. the verapamil post-treatment has been previously reported to prevent reperfusion-induced myocardial injury but functional recovery may be delayed due to the drug's inherent direct myocardial depression effect. in the...

background: stroke is a leading cause of death all around the world, and ischemic stroke is considered to be the most common stroke type. toll-like receptors (tlrs) are important molecules for detection of both pathogen invasion and tissue damage. in this regard, the purpose of this study was to assess the expression level of tlr2 on monocytes in patients with ischemic stroke and to evaluate th...

transient ischemic left ventricular dilation (tid) is a marker of severe and extensive coronary artery disease as well as an increased risk of adverse outcomes. the patients with more severe and extensive ischemia, multivessel-type of perfusion abnormality as well as patients with left anterior descending artery (lad) territory perfusion abnormality have more probability of having tid. evaluati...

background: asphyxia is a perinatal accident with a high mortality rate, therapeutic hypothermia in both head or whole body was suggested as effective therapeutic methods. in this study, we compare these methods in neonates with asphyxia.methods and materials: 16 neonates with asphyxia in two hospitals including alzahra(head hypothermia) and taleghani hospital (total body hypothermia) went unde...

stroke is an important cause of disability and death worldwide, with the majority of strokes occurring in older people. thrombolysis with recombinant tissue plasminogen activator (r-tpa) is the approved treatment for acute ischemic stroke. a major concern of physicians, who treat acute ischemic stroke with recombinant tissue plasminogen activator (r-tpa,) is the risk of intracerebral hemorrhage...

background: impact of high level of uric acid on stroke is still controversial. we conducted this study to investigate the relationship between acute ischemic non-embolic stroke and serum levels of uric acid. methods: this was a case-control study on patients with acute ischemic non-embolic stroke in rafsanjan, iran. the control group consisted of normal persons who were similar to the case gro...