AFMU 5-acetylamino-6-formylamino3-methyluracil ACD Allergic contact dermatitis ACE Angiotensin-converting enzyme AD Atopic dermatitis Ala Alanin Au Gold CA Contact allergy CD Cluster of differentiation CI Confidence interval Cr Chromate CYP Cytochrome P D Deletion DC Dendritic cell DNCB 2,4 dinitrochlorobenzene DTH Delayed-type hypersensitivity DZ Dizygote FLG Filaggrin GST Glutathione S-transf...

BACKGROUND The pathogenesis of irritant contact dermatitis and its modulation according to skin color is not well understood. Reflectance confocal microscopy (RCM) enables high-resolution, real-time, in-vivo imaging of human skin. OBJECTIVE The goal of our study was to use RCM to determine whether susceptibility to irritant contact dermatitis differs between black and white skin. METHODS Pa...

: Occupational contact dermatitis accounts for 90% of all cases of work-related cutaneous disorders. It can be divided into irritant contact dermatitis, which occurs in 80% of cases, and allergic contact dermatitis. In most cases, both types will present as eczematous lesions on exposed parts of the body, notably the hands. Accurate diagnosis relies on meticulous history taking, thorough physic...

BACKGROUND Contact dermatitis (CD) is a common occupational disease. There have been no systematic reviews of CD treatment or prevention. METHODS Multiple databases were systematically searched. Using independent double review and published quality review criteria, articles were rated as good, fair, or poor. Treatment benefit data were tabulated and conclusions were based on the rated strengt...

We present the case of a 42-year-old woman with spina bifida and paraplegia who was referred to us because of chronic discomfort related to erosions and ulcerations of her perineal area, buttocks, and upper posterior thighs (Figure 1). Twenty years previously she had an ileal diversion and urostomy resulting in chronic urethral discharge and diarrhea for 5 years. She required a diaper constantl...

Pedunculated subcutaneous lipoma in the popliteal fossa extending through the superficial fascia causing chronic irritant dermatitis of the adjacent skin with "psoriatic-like" plaque. To the author's knowledge, no similar case has been reported in the literature.

Twelve women in the home help service in Nottingham developed dermatitis after using enzyme detergents. A survey based on a questionary showed an incidence of 5% among those using them. The enzyme appears to act as a primary irritant.