The development of a low temperature kinetic method for the flash photolysis of the compounds of membrane-bound cytochrome a3 with carbon monoxide in the presence of oxygen affords evidence for three categories of functional intermediate compounds of cytochrome a3 and oxygen. The three classes are identified as follows: Compounds of Type A are considered to be "oxy" compounds of the ferrous hem...

Iron is the most abundant metal in the human body and mainly works as a cofactor for proteins such as hemoglobin and various enzymes. No independent life forms on earth can survive without iron. However, excess iron is intimately associated with carcinogenesis by increasing oxidative stress via its catalytic activity to generate hydroxyl radicals. Biomolecules with redox-active sulfhydryl funct...

innumerable percentage of the world population suffers from shortage of vitamins and minerals which is usually called malnutrition. enough perception and access of such essential vitamins and minerals have close relationship with eternity, physical and mental developments, good health, general welfare of individuals and societies. in this research, the fortification of yogurt with iron has been...

Iron is required by most living systems. A great variety of means of acquisition, avenues of uptake, and methods of storage are used by pathogenic fungi to ensure a supply of the essential metal. Solubilization of insoluble iron polymers is the first step in iron assimilation. The two methods most commonly used by microorganisms for solubilization of iron are reduction and chelation. Reduction ...

BACKGROUND Intravenous iron (IVI) therapy is required in patients with end-stage renal disease (ESRD) under chronic haemodialysis (HD). In this in vitro study we investigated the availability and stability of iron hydroxyethyl starch (iron-Hes) compounds in THP-1 cells (macrophage phenotype) and liver cells (HepG2 cells) and compared it with the well-known iron dextran. METHODS The uptake and...

Iron metallodrugs comprise mineral supplements, anti-hypertensive agents and, more recently, magnetic nanomaterials, with both therapeutic and diagnostic roles. As biologically-active metal compounds, concern has been raised regarding the impact of these compounds when emitted to the environment and associated ecotoxicological effects for the fauna. In this work we assessed the relative stabili...

It is well known that cancer might be considered in part to be a preventable disease, highly susceptible to modulation by dietary factors. Polyphenol compounds, which are abundant in fruits, vegetables, seeds and drinks, have been shown to play a potential role as chemopreventive agents. The mechanisms underlying this beneficial effect are not fully understood. Assessing the real impact of such...

It has been shown that the oral administration of ferrous compounds, as compared with ferric salts of iron, resulted in somewhat more rapid absorption of iron from the gastrointestinal tract (results of studieswith radioactive isotopes (l)), and more rapid hemoglobin formation in anemia due to iron deficiency (2). From these results and from the fact that ferrous compounds in general are much m...

Iron (III) phosphate catalyzed condensation reaction of aldehydes, 1,3-dicarbonyl compounds and amuniom acetate refluxing ethanol that remains a common theme in current literature.