This study for the first time achieved an emission spectrometric analysis of the chemiluminescence of flavonoids in the presence of hydrogen peroxide, acetaldehyde and horseradish peroxidase, and revealed that the maximum emission wavelengths (Emax) strictly differ among catechins (E-max 630 nm), theaflavins (Emax 690 nm) and anthocyanins (Emax 675 nm) according to their chemical structures. Th...

objective: the aim of this study was to compare the microtensile bond strengths (μ tbs) of three core materials with one lithium disilicate reinforced ceramic using two resin cements. methods: three core materials (nulite f® (biodental technologies), filtek z250® (3m-espe), prettau-anterior® (zirkonzhan, germany)) were prepared as blocks (10×10×4 mm3) according to the manufacturer’s instruction...

An increasing number of new dielectrics are being reported for the development next-generation ceramic capacitors power electronics used in clean energy technologies. Here, high discharge density (Wdis) ~6.1 J cm−3 with efficiency (η)~72% under a pulsed field (Emax) 410 kV cm−1 is along temperature stability up to 150 °C (Emax = 200 cm−1) 0.5 K0.5Bi0.5TiO3-0.42BiFeO3-0.08Sm(Mg2/3Nb1/3)O3 (KBT-B...

The optical qualities of cutting-edge aesthetic dental ceramics are crucial for great aesthetics and may be impacted by various bleaching methods. objectives this study were to evaluate how home affected the translucency parameter (TP), contrast ratio (CR), total color difference (?E), surface roughness (Ra) ceramics, including innovative ultra-translucent zirconia. three varieties that tested—...

Objectives: The aim of this study was to compare the microtensile bond strengths (µ TBS) of three core materials with one lithium disilicate reinforced ceramic using two resin cements. Methods: Three core materials (Nulite F® (Biodental Technologies), Filtek Z250® (3M-ESPE), Prettau-Anterior® (Zirkonzhan, Germany)) were prepared as blocks (10×10×4 mm3) according...

Although propofol is commonly used for general anesthesia, its direct effects on left ventricular (LV) contractility and energetics remain unknown. Accordingly, we studied the effects of intracoronary propofol on excised cross-circulated canine hearts using the framework of the Emax (a contractility index)-PVA (systolic pressure-volume area, a measure of total mechanical energy)-V(O2) (myocardi...

In animal models, severing the chordae tendineae of the mitral valve reduces the maximum global left ventricular elastance (Emax,g), a load-independent measure of left ventricular systolic performance; moreover, chamber geometry is altered with systolic bulging in the region of the papillary muscle insertions. This suggests that forces transmitted by the mitral apparatus increase the regional v...

The activation of factor X in the presence of antithrombin has been studied in order to determine the parameters that control the area under the resulting factor Xa generation curve. Generation curves were analyzed using a model containing three parameters: the total generation of factor Xa, Emax; the rate of factor Xa generation, expressed as a first-order rate constant, kappa 1; and the rate ...

BACKGROUND It is important to quantify the dose response for a drug in phase 2a clinical trials so the optimal doses can then be selected for subsequent late phase trials. In a phase 2a clinical trial of new lead drug being developed for the treatment of rheumatoid arthritis (RA), a U-shaped dose response curve was observed. In the light of this result further research was undertaken to design ...

The presence of highly conserved amino acid stretches in G protein-coupled receptors (GPCRs) usually predicts an important role in receptor function. Considerable attention has therefore been focused on the involvement of the highly conserved Glu/Asp-Arg-Tyr (E/DRY) motif at the cytoplasmic end of transmembrane domain 3 in the regulation of GPCR conformational states and/or the mediation of G p...