in recent years, ionic liquids have been used in pharmaceutical processes. therefore, having a deep insight into the ion association behavior of ionic liquids in the presence of a drug is of particular importance. so, in this work, the molar conductivities of the ionic liquids, 1-alkyl-3-methylimidazolium bromide, [cnmim]br (n = 4, 6 and 8) in various concentrations of aspirin (asa) in acetonit...

Interfacial regions attached to hydrophobic and hydrophilic surfaces have very low relative permittivities (ε ∼ 3–5), these values induce the formation of ion pairs. A detailed description pairing will be possible only after development adequate experimental probing methods. The scheme described in this work detects pair (or multistage association) water solutions interfacial region. Forces act...

Lane formation dynamics of driven three-dimensional pair-ion plasmas (PIP) is investigated. Extensive Langevin simulation performed to study the influence an external electric field on behaviour PIP system. In our model, one half particles are pushed into direction by force $\boldsymbol {F}_{A}$ while other pulled opposite {F}_{B}$ . We show that if and parallel, system undergoes a non-equilibr...

The objective of this study was to examine whether ion pair complexation with endogenous bile salts in hepatocytes contributes to the preferential biliary excretion of organic cations (OCs). Tributylmethylammonium (TBuMA; mol wt 200) and triethylmethylammonium (TEMA; mol wt 116) were selected as model OCs that exhibit significant and negligible biliary excretion, respectively, in rats. The appa...

We describe the experimental investigation of time-resolved magnetic field effects in exciplex-forming organic donor-acceptor systems. In these systems, the photoexcited acceptor state is predominantly deactivated by bimolecular electron transfer reactions (yielding radical ion pairs) or by direct exciplex formation. The delayed fluorescence emitted by the exciplex is magnetosensitive if the re...

The hydrolysis of amino acid derivatives catalyzed by papain (EC 3.4.4.10) proceeds through the formation of an acyl-thiolenzyme intermediate (cf. refs. [ 1,2] ). The pH-rate profde of the formation of this intermediate displays a bell-shaped curve depending on the ionization of two groups with pK, values of about 4 and 8 [ 1,2]. In the light of the steric structure of the active site of papain...

in this study, a sensitive method of dispersive liquid phase microextraction based on ion-pair combined with the flame atomic absorption spectrometry was proposed for the determination of trace ni(ii) using aliquat 336-chloride as ion pair agent. several factors which have effect on  the microextraction efficiency of ni(ii), such as ph, extraction and dispersive solvent type and their volume, c...