Background: Intraoperative Irradiation Therapy (IORT) refers to the delivery of radiation during surgery and needs computed- thickness target as one most significant factors. Objective: This paper aimed compute design a pattern distributing irradiation uniformly throughout target.Material Methods: The Monte Carlo code was used simulate experimental setup in this simulation study. electron flux ...

The wound healing process after surgery alters the area surrounding the original tumor and around the scar, and the modified microenvironment is more favorable for tumor recurrence. Intraoperative radiotherapy (IORT) is one of the more novel strategies in breast cancer (BC) treatment. Irradiation during surgery has effects on the tumor microenvironment, abrogating the proliferative cascade indu...

Abstract Background Intraoperative radiotherapy (IORT) involves giving a targeted single fraction of high dose radiation to the resection bed. The main advantages are exclusion vulnerable structures from field and ability direct electron beam threatened margins. IORT in pancreatic cancer is not new, with Japanese centres reporting series 1970s. Early reports were exciting, suggesting that was u...

Introduction: Intraoperative electron radiation therapy (IOERT) is one of the cancer treatment techniques that delivers high doses to tumor bed during surgery. IOERT can be performed by either conventional LINACs or dedicated IORT accelerators such as LIAC (Light Intraoperative Accelerator). Two types of applicators can be used with LIAC dedicated accelerator including conventi...