intraosseous movement of an unerupted tooth across the midline of the jaw is known as dental transmigration. this infrequent event is mostly found in the mandibular canines. there are four new cases of mandibular canine transmigration presented here. the literature on this anomalous phenomenon is also reviewed.

introduction multiple dentigerous cysts are rare and mostly associated with syndromes. case presentation the present case report is unique, as the dentigerous cysts enclosed the lateral incisor, canine, first and second premolars of the mandible and were accompanied by a complex odontoma, instead of first mandibular molar. conclusions multiple unilateral nosyndromic dentigerous cysts with compl...

Dynamin is a well-known regulator of synaptic endocytosis. Temperature-sensitive dynamin (shi(ts1)) mutations in Drosophila melanogaster or deletion of some of the mammalian Dynamins causes the accumulation of invaginated endocytic pits at synapses, sometimes also on bulk endosomes, indicating impaired membrane scission. However, complete loss of dynamin function has not been studied in neurons...

We have examined the expression of caveolin in MDCK cells under conditions that vary cellular cholesterol concentration. Caveolin mRNA levels dropped to one-sixth of control levels after treatment with simvastatin, an inhibitor of cholesterol synthesis, or beta-trimethyl cyclodextrin (CD), a cholesterol sequestering drug. Both simvastatin and CD treatment decreased total cellular cholesterol le...

this report presents a rare case of bi-rooted primary maxillary canines. a 6-year-old girl presented at the department of pediatric dentistry, faculty of dentistry, mashhad university of medical sciences, iran, with the chief complaint of pain in the lower right quadrant of her dentition. radiographic examination revealed bifurcation of primary maxillary canine roots. this report discusses the ...