It is extremely rare for cancer to present as an intramedullary spinal cord metastasis. The authors report on a case of a 74-year-old woman presenting with progressive tetraparesis to metastatic colon adenocarcinoma in the spinal cord. A review of the literature reveals that intramedullary localization is associated with a very short life expectancy, with a median survival of 3 4 months from th...

Prophylactic intramedullary fi xation of impending pathologic fractures is an important preventative technique. Intramedullary rods provide longitudinal structural support, protecting weakened cortices from fracture displacement, providing pain relief, and allowing for restoration of function.1,2 In the femur, prophylactic stabilization of an impending fracture in a metastatic tumor population ...

Intramedullary spinal cord tuberculoma in a young, homosexual man with AIDS was detected with the use of MR and confirmed pathologically. MR findings were similar to those seen in other intramedullary lesions, eg, astrocytoma, ependymoma, hemangioblastoma, metastasis, lymphoma, and opportunistic infections. Delineation of the lesion improved with administration of Gd-DTPA; enhancement of the le...

Primary intramedullary spinal cord tumors are rare in domestic animals and extremely rare in cats [l, 51. This report concerns a primary intramedullary spinal cord tumor in a cat. An 1 1-year-old spayed female domestic shorthair cat was presented to the University of Minnesota Teaching Hospital in lateral recumbency with tetraparesis. All laboratory parameters (electroencephalogram, cerebrospin...

To assess a possible role in tumor progression, the occurrence and type of K- and N-RAS mutations were determined in purified tumor cells, including samples from patients with premalignant monoclonal gammopathy of undetermined significance (MGUS), multiple myeloma (MM), and extramedullary plasma cell (PC) tumors (ExPCTs). Immunophenotypic aberrant PCs were flow sorted from 20 MGUS, 58 MM, and 1...