BACKGROUND In-stent restenosis due to intimal hyperplasia is an important clinical problem. Animal models of stent injury are limited by inconsistent arterial responses to stenting, and less intimal hyperplasia than diseased human vessels. To address these issues, we aimed to compare the degree of intimal hyperplasia in stented rabbit jugular-carotid interposition grafts (vein grafts) versus st...

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The current study describes the histopathology of angiographic chronic total occlusions including residual lumen patency, intimal plaque composition, patterns of neovascular channel formation, intimal plaque calcification, and cellular inflammation, analyzed according to occlusion duration and intimal plaque type (fibrocalcific vs. lipid laden vs. mixed). Histologic findings are related to prev...

Intimal hyperplasia is one of the prominent failure mechanisms for arteriovenous fistulas and arteriovenous access grafts. Human tissue-engineered vascular grafts (TEVGs) were implanted as arteriovenous grafts in a novel baboon model. Ultrasound was used to monitor flow rates and vascular diameters throughout the study. Intimal hyperplasia in the outflow vein of TEVGs was assessed at the anasto...

BACKGROUND AND PURPOSE Few longitudinal data about early atherosclerotic lesions of the carotid arteries are available in general populations. The main purpose of this study was to investigate risk factors for development and regression of intimal-medial thickening and atheromatous plaques. METHODS Initial and 2-year examinations of the carotid arteries with high-resolution B-mode ultrasonogr...

OBJECTIVES To evaluate the feasibility of dose-modulated retrospective ECG-gated thoracoabdominal aorta CT angiography (CTA) assessing abdominal aortic intimal flap motion and investigate the motion characteristics of intimal flap in acute aortic dissection (AAD). MATERIALS AND METHODS 49 patients who had thoracoabdominal aorta retrospective ECG-gated CTA scan were enrolled. 20 datasets were ...

Treatment of arterial traumatic intimal lesions is controversial due to its unknown natural history. Current therapeutical options include arterial reconstruction and clinical observation. The idea of using stents to correct intimal flaps is based on their use to correct dissections, flaps, and arterial irregularities after angioplasty. We report the successful treatment of a traumatic intimal ...

Aortic intimal sarcoma is rare and the prognosis is very poor. We experienced a case of ruptured aortic intimal sarcoma in the descending aorta. A 69-year-old man underwent an emergency operation for the rupture of descending aorta. The postoperative course was uneventful. The histological examination of aortic wall showed aortic intimal sarcoma. The patient developed a local recurrence and abd...

Figure 1: An intimal flap obstructing orifices of the arch vessels (A). Another flap was seen in the Valsalva sinus and outflow of the left ventricle (B, arrow). There was no intimal flap in the ascending aorta (C). Figure 2: Transoesophageal echocardiography showed the prolapse of the intimal flap into both the left ventricle (systolic and diastolic phase; Left, arrows) and the aortic arch (Ri...