Chelatococcus daeguensis TAD1 is a themophilic bacterium isolated from a biotrickling filter used to treat NOx in Ruiming Power Plant, located in Guangzhou, China, which shows an excellent aerobic denitrification activity at high temperature. The complete genome sequence of this strain was reported in the present study. Genes related to the aerobic denitrification were identified through whole ...

Sarcoma 37 cells grew more rapidly in castrated male mice than in controls of the same genotype; however, this effect of castration was dependent on the host genotype. Among inbred YS/Wf mice, tumor weight was increased only in castrated yellow Ay/a males and not in the comparable black a/a males. In contrast, mean tumor weight was increased in both yellow Avy/a and black a/a castrated males of...

Title: Oral intake of Phenylbutyrate and vitamin D3 upregulates the Cathelicidin LL-37 in human macrophages: A dose finding study for treatment of tuberculosis Authors: Akhirunnesa Mily ([email protected]) Rokeya Sultana Rekha ([email protected]) SM Mostafa Kamal ([email protected]) Evana Akhtar ([email protected]) Protim Sarker ([email protected]) Zeaur Rahim ([email protected]) Gudmund...

In the course of our chemical screening program for new secondary metabolites, we isolated new compounds JBIR-37 (1) and -38 (2) from a culture broth of the marine sponge-derived fungus, Acremonium sp. SpF080624G1f01. The structures of 1 and 2 were determined to be di- and mono-O-beta-D-glucopyranosyloxy-4-(1,1-dimethyl-2-propenyl)benzene on the basis of extensive NMR and MS spectroscopic data,...

Here we show that keratinocytes in psoriatic lesional skin express increased Toll-like receptor (TLR) 9 that similarly localizes with elevated expression of the cathelicidin antimicrobial peptide LL-37. In culture, normal human keratinocytes exposed to LL-37 increased TLR9 expression. Furthermore, when keratinocytes were exposed to LL-37 and subsequently treated with TLR9 ligands, such as CpG o...

Antimicrobial peptide IG-25 (a truncated version of LL-37 of the cathelicidin family) tethering an azido-capped poly(ethylene glycol) chain at the N-terminus was site-specifically attached to alkynyl-terminated polymerized liposomes using copper catalyzed "click" reaction, leading to an 18 fold enhancement in efficacy against Pseudomonas aeruginosa when compared to LL-37 without any increase in...