نتایج جستجو برای: interleukin 5
تعداد نتایج: 1299019 فیلتر نتایج به سال:
Asthma is a chronic inflammatory disorder of the airways that leads to acute symptoms, exacerbations and sometimes, for a small part of the asthmatic population, fatal or near-fatal exacerbations. This as yet significant minority of individuals present with severe asthma and have persisting daily symptoms, and exacerbations despite compliance with high doses of inhaled steroids and additional t...
Interleukin-5 (IL-5) is a critical cytokine for the maturation of eosinophil precursors to eosinophils in the bone marrow and those eosinophils then accumulated in the lungs during asthma. We have studied anti IL-5 antibodies on allergic responses in mice, guinea pigs and monkeys and are extending this experiment into humans with a humanized antibody. In a monkey model of pulmonary inflammation...
Epithelial cells are major targets of permissive infection by human cytomegalovirus (HCMV) in vivo during acute infection, but little is known about the viral factors that influence the permissiveness of epithelial cells for HCMV. The aim of the present study was to investigate the interleukin-8 (IL-8)-inducing capacities of HCMV clinical isolates of different origins by comparison of the repli...
background: endometriosis is a frequent gynecologic disease with a severe impact on the quality of life in the affected women; its pathogenesis is yet to be fully understood, with an altered immunity as a possible key factor. the present study aimed to investigate the serum anti-inflammatory cytokine profile in the patients with endometriosis compared with the healthy controls. materials and me...
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