Effects of ?-cyclodextrin, ?CD, on refolding of lysozyme was investigated at pH 12 employing isothermal titration calorimetry (ITC) at 300K in 30mM Tris buffer solution. ?CD was employed as an anti-aggregation agent and the heats obtained for lysozyme+?CD interactions are reported and analyzed in terms of the extended solvation model. It was indicated that there are two sets of identical and no...

In an order-of-addition (OofA) experiment, the response is a function of addition order components. The key objective OofA experiments to find optimal addition. most popularly used model for perhaps pairwise ordering (PWO) model, which assumes that can be fully accounted by Recently, PWO has been extended adding interactions factors, account variations caused sets three or more components, wher...

Although interaction effects can be exploited to improve predictions and allow for valuable insights into covariate interplay, they are given limited attention in analysis. Interaction forests a variant of random categorical, continuous, survival outcomes that explicitly models quantitative qualitative bivariable splits performed by the trees constituting forests. The new effect importance meas...