Type 2 diabetes mellitus (T2DM), a disease on the rise and with huge economic burden to health care systems around the globe, results from defects in insulin action (termed insulin resistance) combined with impaired insulin secretion. Current methods of prevention and treatments for insulin resistance and T2DM are lacking in number and efficacy and, therefore, there is a need for new preventati...

BACKGROUND Urtica dioica has been used as antihypertensive, antihyperlipidemic and antidiabetic herbal medicine. The purpose of this study was to study the effect of hydroalcoholic extract of Urtica dioica on fructose-induced insulin resistance rats. METHODS Forty male Wistar rats were randomly divided into five groups including control, fructose, extract 50, extract 100 and extract 200. The ...

Barberry fruit is consumed in different forms including dried fruit, juice, jam and marmalade in Iran. This fruit is also used as a food additive (flavoring and colorant) in soup and rice dishes. In present study, antioxidant activities of acetone, ethanol and water (infusion and decoction) extracts of barberry (Berberis vulgaris) fruit were investigated using 2,2-azinobis-3-ethylbenzo...

BACKGROUND Rhodiola species have been used for asthenia, depression, fatigue, poor work performance and cardiovascular diseases, all of which may be associated with insulin resistance. To disclose the underlying mechanisms of action, the effect of Rhodiola crenulata root (RCR) on insulin resistance was investigated. METHODS Male Sprague-Dawley rats were treated with liquid fructose in their d...

PCOS (Polycystic Ovarian Syndrome) is associated with insulin resistance, obesity and disorders of lipid metabolism as well as infertility. Fenugreek seeds extract is successfully used in lowering blood glucose. Metformin has also the same effect but in a different way. The aim of this study was the assessment of fenugreek effects on insulin resistance in women with PCOS. This was a prospective...

BACKGROUND Fructose is widely used as a food ingredient and has potential to increase oxidative stress. Moreover, the beneficial health effects of medicinal plants are frequently attributed to their potent antioxidant effects. OBJECTIVES The present study was aimed to explore the effects of garlic (Allium sativum) extract on insulin resistance, inflammation and oxidative stress in male wistar...

introduction: aim of present research was to review the effect of resistance training on glycemic indexes of streptozotocin induced diabetic rats. methods: for this purpose 36 male rats with weight 308/82±29/57 selected. one week after induction of diabetes diabetic rats were randomly divided into two groups including resistance training and control and healthy rats divided in to two groups inc...

d-galactose induces pancreatic disorder along with aging mouse model. vitex agnus-castus (vac) has potential pancreatic protective effect. hence, this study was designed to evaluate the hypoglycemic and pancreas protective effects of vac hydroalcoholic extract in d-galactose-induced aging female mice. in the present experimental study, 72 adult female naval medical research institute (nmri) mic...