نتایج جستجو برای: injectable drugs

تعداد نتایج: 234110  

Journal: :Expert opinion on drug safety 2016
Anthony J Garcia-Prats H Simon Schaaf Anneke C Hesseling

INTRODUCTION A growing number of children globally are being treated for multidrug-resistant tuberculosis (MDR-TB). The second-line injectable antituberculosis medications amikacin, kanamycin and capreomycin, traditionally a mainstay of MDR-TB treatment, cause important adverse effects including permanent sensorineural hearing loss, nephrotoxicity, electrolyte abnormalities, injection pain and ...

Background and Aim:  Drug prescription is an important part of pharmacotherapy; therefore, inattention to the principle of drug prescription can cause problems such as incorrect treatment, unsuccessful or incomplete, and force higher cost to patients and society. While prescribing and rational use of drugs can prevent the loss of national capital and community health promotion through imp...

2012
Liandong Hu Hailei Zhang Weihua Song

In recent years, there has been a great deal of interests in developing sustained-release systems which can prolong the therapeutic effect, decrease adverse side effects, and reduce administration frequency. Nowadays, the oral sustained-release preparations account for a larger market share comparing to other sustained-release forms, mainly because of its noninvasive pain-free administration. H...

Journal: :The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2014
A P Trollip D Moore J Coronel L Caviedes S Klages T Victor E Romancenco V Crudu K Ajbani V P Vineet C Rodrigues R L Jackson K Eisenach R S Garfein T C Rodwell E Desmond E J Groessl T G Ganiats A Catanzaro

OBJECTIVE To establish breakpoint concentrations for the fluoroquinolones (moxifloxacin [MFX] and ofloxacin [OFX]) and injectable second-line drugs (amikacin [AMK], kanamycin [KM] and capreomycin [CPM]) using the microscopic observation drug susceptibility (MODS) assay. SETTING A multinational study conducted between February 2011 and August 2012 in Peru, India, Moldova and South Africa. DE...

Journal: :The Journal of the Association of Physicians of India 2014
Bharat Purandare

INTRODUCTION Many tuberculosis (TB) patients have resistance patterns intermediate between multidrug-resistant (MDR) and extensively drug-resistant (XDR). We defined MDR+ as resistance to rifampin (RMP), isoniazid (INH) and at least one more drug other than fluoroquinolone (FQ) and second-line injectable agent (IA); and Pre-XDR as MDR with additional resistance to either FQ or IA. Such patients...

2015
F. Scarlett Thomas Joseph B. Stanford Jessica N. Sanders Shawn E. Gurtcheff Mark Gibson Christina A. Porucznik Sara E. Simonsen

BACKGROUND Many women throughout the world have history of subfertility (resolved or unresolved), but much remains unknown about services and treatments chosen. METHODS We developed a mixed-mode fertility experiences questionnaire (FEQ) in 2009 through literature review and iterative pilot work to optimize question format and mode of administration. The focus of the FEQ is to collect data ret...

2015
Woojun Kim Manuella Edler Zandoná Su-Hyun Kim Ho Jin Kim

Classical multiple sclerosis (MS) treatments using first-line injectable drugs, although widely applied, remain a major concern in terms of therapeutic adherence and efficacy. New oral drugs recently approved for MS treatment represent significant advances in therapy. The oral route of administration clearly promotes patient satisfaction and increases therapeutic compliance. However, these drug...

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