نتایج جستجو برای: inherited inferiority
تعداد نتایج: 34895 فیلتر نتایج به سال:
Individuals are recruited during an accrual period of R years (or months or days). They are followed for an additional period of time until a total of T years is reached. Hence, the follow-up period is T-R years. At the end of the study, the non-inferiority logrank test is conducted at significance level α with power 1− β . Under the proportion hazards assumption, the hazard ratio HR = h2 / h1 ...
INTRODUCTION There is currently little evidence for the optimal dosing strategy of four-factor prothrombin complex concentrates (PCC) in vitamin K antagonist (VKA)-related bleeds. The generally accepted dosing strategy is the use of a variable dose calculated using patient-specific characteristics as per manufacturer's instruction. However, evidence exists that the use of a fixed low dose of 10...
OBJECTIVE The aim of this prospective multicenter randomized controlled trial was to compare the efficacy of silver nitrate cauterization against that of topical steroid ointment in the treatment of neonatal umbilical granuloma. METHODS An open-label, non-inferiority randomized controlled trial was conducted from January 2013 to January 2016. The primary endpoint for the silver nitrate cauter...
Specific antibodies to human fetal hemoglobin were prepared and, after conjugation with a fluorescent dye, were used to determine the distribution of Hb F-containing cells in blood smears from normal adults and individuals with hereditary and acquired conditions associated with abnormal levels of Hb F. The mean proportion of F-cells in normal persons was 2.7% +/- 1.4%, with a range of 0.5%-7.0%...
We propose a new nonparametric method for assessing non-inferiority of an experimental therapy compared to a standard of care. The ratio E R of true median survival times is the parameter of interest. This is of considerable interest in clinical trials of generic drugs. We think of the ratio E R m m of the sample medians as a point estimate of the ratio E R . We use the Fieller-Hinkley ...
Background Treatment effect is traditionally assessed through either superiority or non-inferiority clinical trials. Investigators may find that because of safety concerns and/or wide variability across strata of the superiority margin of active controls over placebo, neither a superiority nor a non-inferiority trial design is ethical or practical in some disease populations. Prior knowledge ma...
You You ' ' ve heard a lot about NI trials already, so I ve heard a lot about NI trials already, so I ' ' ll try not to ll try not to repeat. The critical issues are, by now known to you: repeat. The critical issues are, by now known to you: 1. In most cases NI trials pose inferential problems, but 1. In most cases NI trials pose inferential problems, but you use them when you have no choice, i...
Homeopathy is a complementary and integrative medicine used in depression, The aim of this study is to investigate the non-inferiority and tolerability of individualized homeopathic medicines [Quinquagintamillesmial (Q-potencies)] in acute depression, using fluoxetine as active control. Ninety-one outpatients with moderate to severe depression were assigned to receive an individualized homeopat...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید