conclusions rats fed with a 30% calorie-restricted diet in comparison with to ad libitum fed controls for 8 days had significantly more prominent regression of inflammation. results decline of both body weight and paw volume was significantly more prominent in the case than in the control rats within the study period (p < 0.001 and < 0.001, respectively). paw volume decrease was more prominent ...

background : we report experimental myocardial infarction by occluding coronary arteries in ovine models. methods: twelve ewes were included in the study. after the chest was opened by left lateral thoracotomy incision, the second diagonal branch of the left anterior descending coronary artery was ligated at a point approximately 40% distant from its base. prophylactic antiarrhythmics were admi...

asthma is a chronic inflammatory disease of the airway with extensive airway remodeling. the ethical issues associated with the studies in asthmatic patients, required development of animal model of asthma. animal models of asthma can provide valuable information on several features of asthma pathogenesis and treatment. although these models cannot carry out all clinical features, they are valu...

conclusions in conclusion, our observations indicated that pcdna3.1 (+)-hbv1.3c was superior to aav/hbv plasmid for establishment of persistent hbv infection by hi, in vivo, and this mouse model could be useful for studies of hepatitis virology and for the development of innovatory treatments for hbv infections. results in 60% of the mice injected with pcdna3.1 (+)-hbv1.3c, hbsag, hbeag, hbcag ...

conclusions according to the liver microrna data of chinese tree shrew, characteristics of the mir-122 and let-7 families further highlight the suitability of tree shrew as the animal model in hcv research. objectives this study aimed to construct a liver microrna (mirna) data of the tree shrew. materials and methods three second filial generation tree shrews were used in this study. total rna ...

Animal models have become standard tools for the study of a wide array of human infectious diseases. Although there are no true animal reservoirs for Mycobacterium tuberculosis, many different animal species are susceptible to infection with this organism and have served as valuable tools for the study of tuberculosis (TB). The most commonly used experimental animal models of TB are the mouse, ...