نتایج جستجو برای: induced diabetes
تعداد نتایج: 1246171 فیلتر نتایج به سال:
objective(s):pentoxifylline is an immunomodulatory and anti-inflammatory agent and is used in vascular disorders. it has been shown that pentoxifylline inhibits proinflammatory [d1] cytokines production. the purpose of this study was to investigate the therapeutic effects of pentoxifylline on the treatment of autoimmune diabetes in mice. materials and methods: diabetes was induced by multiple l...
diabetes is one of the most common metabolic disorders and is interrelated to oxidative stress-induced diseases. according to the role of dietary antioxidants in control and prevention of diabetes, this study was aimed to evaluate the effect of green tea extract on serum glucose levels and serum and hepatic total antioxidant capacity (tac) and lipid (mda) in diabetic rats. experimental diabetes...
Background and Aim: Diabetes can lead to reduced fertility in men by production of free radicals. Crocin (the effective component of saffron) with its antioxidant property can be effective in elimination of free radicals. We evaluated the effects of crocin on the reproductive parameters of the STZ –induced diabetic male Wistar rats. Materials and Method: Rats were made diabetic with...
Background & Aims: Type 1 diabetes is an autoimmune condition associated with the T-cell–mediated destruction of Pancreatic β cells. Vitamin A (retinol) and its metabolites (such as all-trans retinoic acid (ATRA)) have a variety of biological activities including immunomodulatory action in a number of inflammatory and autoimmune conditions. The purpose of this study was to investigate the e...
diabetes mellitus is associated with distribution of cognitive functioning. hyperglycemia diabetes mellitus is associated with distribution of cognitive functioning. hyperglycemia induced oxidative stress has been proposed as a cause of memory complications of diabetes including cognitive impairment. the aim of this study was to examine total green tea extract (tgte), a potent free radical scav...
Introduction: Mitochondrial dynamic disorders are attributed to many diseases such as diabetes. MFN2 and OPA-1 proteins are the main regulators of fusion, and DRP1 is the essential protein regulating mitochondrial fission. Increasing or decreasing the expression of relevant genes will cause an imbalance between these two processes. This study evaluated the effect of six weeks of aerobic trainin...
Background and purpose: Diabetes is a health problem worldwide with increasing prevalence in most countries. Nephropathy is a common microvascular complication of diabetes. Diabetes is directly associated with oxidative stress and mitochondrial damage that result in renal tissue damage. This study evaluated the efficiency of nanoceria in attenuation of oxidative damage in renal isolated mitocho...
Polysaccharide –based hydro gels from marine algae are attractive materials for biomedical applications which include polyfunctionality and biodegradability. There were reports of many based hydrogels their in diabetic neuropathy. The present study aims to investigate the progressive effects injectable Chitosan-Ulva lactuca polysaccharide hydrogel (C-UL hydrogel) on experimentally induced neuro...
Diabetes, which is mainly characterized by increased apoptosis and dysfunction of beta (β) cells, a metabolic disease caused impairment pancreatic islet function. Previous studies have demonstrated that death-associated protein kinase-related apoptosis-inducing kinase-2 (Drak2) involved in regulating β cell survival. Since natural products multiple targets often are multifunctional, making them...
background: diabetes is one of the most common metabolic disorders and is related to oxidative-stress-induced diseases. given the role of dietary antioxidants in the control and prevention of diabetes, this study aimed to examine the effects of sesame butter versus sesame oil on the serum levels of glucose, lipid profile, and oxidative stress biomarkers in diabetic rats. methods: forty male alb...
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