The way chromatin is organized inside the nucleus of eukaryotic cells is a key factor in gene control. It seems that the cell is able to transcriptionally regulate genomic loci by changing their local environment in the nucleus. Such environment may inhibit, permit or boost gene activity. To unravel underlying molecular mechanisms it is essential to develop techniques that allow the simultaneou...

In technical drawings and medical drawings/maps it is often common to explain certain features of the drawing by blocks of text that are arranged on its boundary. Bekos et. al. introduced the term boundary labelling to describe this special type of labelling and presented algorithms for automatic boundary labelling. BLer is a prototype tool aiming to automate the boundary labelling process. It ...

For positive integers k and d ≥ 2, a k-S(d, 1)-labelling of a graph G is a function on the vertex set of G, f : V (G) → {0, 1, 2, · · · , k− 1}, such that |f(u)− f(v)|k ≥ { d if dG(u, v) = 1; 1 if dG(u, v) = 2, where |x|k = min{|x|, k − |x|} is the circular difference modulo k. In general, this kind of labelling is called the S(d, 1)-labelling. The σdnumber of G, σd(G), is the minimum k of a k-...

Luminescent lanthanide chelates have been used to label antibodies in time-gated luminescence (TGL) bioimaging. However, it is a challenging task to label directly an antibody with lanthanide-binding ligands and achieve control of the target ligand/protein ratios whilst ensuring that affinity and avidity of the antibody remain uncompromised. We report the development of a new indirect detection...

Lymphoid tissue of the endometrium was analysed by histological, immunohistological, and electron microscopical methods in 10 healthy uteri. A panel of monoclonal antibodies recognising macrophages (OKMI), HLA-DR antigen, B lymphocytes, T lymphocytes and their subsets, and dendritic reticulum cells was used in a two stage indirect immunoperoxidase labelling technique. Endometrial lymphoid tissu...

Deterministic annealing and relaxation labeling algorithms for classiication and matching are presented and discussed. A new approach |self annealing|is introduced to bring deterministic annealing and relaxation labeling into accord. Self annealing results in an emergent linear schedule for winner-take-all and assignment problems. Also, the relaxation labeling algorithm can be seen as an approx...

In this paper, we tackle the problem of matching of objects in video in the context of the rough indexing paradigm. The approach developed is based on matching of region adjacency graphs (RAG) of pre-segmented objects. In the context of the rough indexing paradigm, the video data are of very low resolution and segmentation is consequently inaccurate. Hence the RAGs vary with the time. The contr...

A novel approach to junction detection using an explicit line finder model and contextual rules is presented. Contextual rules expressing properties of 3D-edges (surface orientation discontinuities) limit the number of line intersections interpreted as junctions. Probabilistic relaxation labelling scheme is used to combine the a priori world knowledge represented by contextual rules and the inf...