Nonalcoholic fatty liver disease (NAFLD) is emerging as an important cause of liver disease in India. Epidemiological studies suggest prevalence of NAFLD in around 9% to 32% of general population in India with higher prevalence in those with overweight or obesity and those with diabetes or prediabetes. Clinicopathological studies show that NAFLD is an important cause of unexplained rise in hepa...

Most of the existing total knee arthroplasty (TKA) implants are designed to suit the knee anatomy of the Western population. Studies have shown that there are striking variations in knee morphology between the Asian and Western population. We conducted a case-control study to investigate the anthropometry of the Indian arthritic knees using three dimensional knee models and evaluated them morph...

background: we aimed to determine the frequency of liver copper storage diseases in iranian children with cryptogenic chronic liver disease (cld). materials and methods: one-hundred and twenty children (52 girls, 70 boys; age range: 3 months-14 years) with cld who attended children's medical center in tehran, iran during the years 1997 through 1999, were enrolled. all viral, metabolic and autoi...

Conventional antipsychotic agents are not effective against negative symptoms of schizophrenia and are also noted for their extrapyramidal side effects. Risperidone is a noval antipsychotic agent whose dual antagonism of dopamine and serotonin receptors is believed to underlie its efficacy against negative symptoms and the low incidence of extrapyramidal side effects. An open, non-comparative s...

We report results of HLA-A, B, C, and DR typing in groups of white Caucasians of English descent and black West Indians of African descent with sarcoidosis. In the English patients we found a significantly increased frequency of Cw7, which was not found in the West Indian patients. Our results also suggest that DR3 and, in particular, inheritance of the B8/Cw7/DR3 haplotype is associated with g...

The study aimed to investigate differential expression of targeted inflammatory-immune responsive genes [LTA, LTB, TNFSF4, TNFSF11/RANKL, TNFSF13, TNFSF13B, TNFRSF11B/ Osteoprotegerin; OPG and GFPT1/GFA ] in gingival tissues of bronchiectasis patients having chronic periodontitis in North central Indian population. Gingival tissues were collected from 30 systemically healthy chronic periodontit...

Diet has always played a major role in the management of diabetes. In the pre-insulin era diet played a dominant role in the management of diabetes. Even after the discovery of insulin and several oral hypoglycemic agents diet forms the sheet anchor of treatment. The dietary approaches have varied from time to time. The pendulum has swing from the starvation diets of Allen, to restriction of ca...

background: uveitis refers to diseases characterized by intraocular inflammation of the uveal tract. anterior uveitis is a common ocular disease characterized by inflammation of the iris and the ciliary body. objectives: to establish the frequency of hla-b27- positive uveitis in asian indian population, study their clinical profile and compare it with other reports in literature. methods: we re...

BACKGROUND In 1998 ethnic minorities comprised 28% of the US population, and India is the third most common country of origin for immigrants. Many recently immigrated South Asian Indian patients are seen in health care settings in the United States. To deliver health care effectively to these patients, it is helpful for physicians to understand common cultural beliefs and practices of South Asi...