We studied the reaction of phenyl radicals (C(6)H(5)) with 1,3-butadiene (H(2)CCHCHCH(2)) exploiting a high temperature chemical reactor under combustion-like conditions (300 Torr, 873 K). The reaction products were probed in a supersonic beam by utilizing VUV radiation from the Advanced Light Source and by recording the experimental PIE curves at mass-to-charge ratios of m/z = 130 (C(10)H(10)(...

1. The metabolism of cis-indane-1,2-diol, trans-indane-1,2-diol, indene epoxide and 2-hydroxyindan-1-one in rats has been studied. The substances were administered to the animals by subcutaneous injection. 2. The urine of the dosed animals was examined for the presence of free and conjugated cis- and trans-dihydrodiols, and for each compound it was possible to isolate both cis and trans forms o...

Tandem reactions of cis-2-acyl-1-alkynyl-1-aryl cyclopropanes tuned by gold(i) and silver(i) catalysts are described, which afford selectively the key pyran-fused indene cores and the 2,4,6-trisubstituted phenols in good yields, respectively.

In the title compound C(37)H(32)Cl(2)N(2)O(4), the unsubstituted pyrrolidine ring shows a twist conformation whereas the substituted pyrrolidine ring shows an envelope conformation. The dimeth-oxy benzene ring is perpendicular to the tetra-lone ring, making a dihedral angle of 89.94 (5)°. Mol-ecules are linked into centrosymmetric dimers by N-H⋯O hydrogen bonds and the crystal structure is stab...

A series of amino derivative of 1-indene and 9-fluorene have been synthesized from their corresponding iminium salt, generated in situ in the concentrated ethereal lithium perchlorate solution, and 1-indenyl or 9-fluorenyl anions. The yields of the reactions depend on the kind of anion. Addition of 1-indeny anion to the iminium salt gives the amino derivative of 1-indene, while addition of fluo...

The title compound, C20H20O3, contains two fused rings with a quaternary carbon centre connecting p-toluoyl and eth-oxy-carbonyl groups. The dihedral angle between the fused benzene ring and the three-C-atom plane (derived from O=C-C-C=O) is 82.5 (4)°, whereas the dihedral angle between the planes of the benzene rings is 53.4 (2)°. In the crystal, molecules are linked via C-H⋯Oester hydrogen bo...

A radical Smiles rearrangement strategy for allowing an unprecedented [3 + 2]/[3 2] carboannulation of dienynes with arylsulfonyl chlorides using cheap copper catalysis is described.

The Pyrrolizidine Alkaloids (PAs) are the chemicals which are found in various plant species throughout the world. Pyrrolizidine alkaloids (PAs) are secondary metabolites those have been evolved as a powerful means in the plant defensive system against herbivores. Several studies are being performing to detect presence of PAs in the food and feed which are obtained from plants through direct or...

The atypical, non-toxic pyrrolizidine alkaloid tussilagin and its isomers have been found in only a few plants of the Asteraceae (Roeder et al., 1981,1984; Passreiter et al., 1992; Roeder et al., 1993; Sener and Etgun, 1996; Wernery et al., 1997; Passreiter, 1998). Their possible biosynthetic precursor pyrrolidine-2-acetic acid and its methylester were isolated and identi"ed together with the p...