background and aims:  myasthenia gravis (mg) is a chronic autoimmune disorder of neuromuscular transmission resulting in muscle weakness. while mg reportedly occurs in all ethnic groups, relative differences in disease prevalence are yet to be determined. the aim of this study was evaluation  of incidance and other disorders with it in kerman province of iran. methods: all patients with mg that...

Data from the International Collaborative Gaucher Group Gaucher Registry were analysed to assess the relationship between enzyme replacement therapy with imiglucerase (ERT) and incidence of avascular necrosis (AVN) in type 1 Gaucher disease (GD1), and to determine whether the time interval between diagnosis and initiation of ERT influences the incidence rate of AVN. All patients with GD1 enroll...

OBJECTIVE To determine whether serum concentrations of long chain n-3 polyunsaturated fatty acids (LCn3PUFAs) contribute to the difference in the incidence rate of coronary artery calcification (CAC) between Japanese men in Japan and white men in the USA. METHODS In a population based, prospective cohort study, 214 Japanese men and 152 white men aged 40-49 years at baseline (2002-2006) with c...

PURPOSE To investigate the incidence rate of tranexamic acid (TXA)-associated seizures. METHODS Two electronic databases (Medline and Embase) were searched. We looked for additional studies in the references of all identified publications. The cutoff day was 2015 Dec 06. Two authors independently reviewed the titles and abstracts of the publications identified firstly. Odds ratio (OR) and 95%...

BACKGROUND Orthostatic hypotension causes ≈80 000 hospitalizations per year in the United States. Treatments for orthostatic hypotension include fludrocortisone, a mineralocorticoid analog that promotes sodium reabsorption; and midodrine, an α-1 adrenergic agonist that is a direct vasoconstrictor. Although both medications are used to treat orthostatic hypotension, few studies have compared the...

BACKGROUND AND OBJECTIVES The prevalence of nephrolithiasis in the United States has increased substantially, but recent changes in incidence with respect to age, sex, and race are not well characterized. This study examined temporal trends in the annual incidence and cumulative risk of nephrolithiasis among children and adults living in South Carolina over a 16-year period. DESIGN, SETTING, ...

conclusions: using these factors, nephrologists may predict the occurrence of graft loss or death. if the probability of graft loss was higher, physicians can decrease the immunosuppressive medications dosage to decrease the incidence of graft loss. patients and methods: fine-gray model was used for 266 cases with post-transplant malignancy in iran. these patients were followed-up from the diag...

background: evidence shows that the mortality rate of esophageal cancer (ec) in ardabil province is among the highest worldwide. studies on the epidemiological profile of ec in ardabil are scarce. we aim to study the characteristics of ec in ardabil using data from the recently established ardabil cancer registry (acr). materials and methods: this study has been accomplished based on data colle...

OBJECTIVE To compare the incidence of cardiovascular events and mortality in patients with type 2 diabetes mellitus treated with sitagliptin or non-sitagliptin comparators. METHODS A post hoc assessment of cardiovascular safety in 14,611 patients was performed by pooling data from 25 double-blind studies, which randomised patients at baseline to sitagliptin 100 mg/day or a non-sitagliptin com...