Background: Mitochondria are the most aboudent and small essential organelles found in eukaryotic cells. These are semiautonomous organelles for the production of cellular ATP that through its various biochemical pathways. The primary pathway for ATP production is OXPHOS via the electron transfer chain (ETC) which is encoded by nuclear DNA and mtdna genomes. Mitochondria consist of double stran...

INTRODUCTION Some unexplained infertile couples may have fertilization failure; the in vitro fertilization (IVF) with high insemination concentration (HIC) and intracytoplasmic sperm injection (ICSI) were reported to give better fertilization rate when compared to standard IVF procedure. OBJECTIVE To compare the fertilization rate, abnormal fertilization rate, total fertilization failure rate...

As in vitro fertilization (IVF) and other reproductive technologies become increasingly prevalent, the legal and bioethical issues that inevitably accompany these new technologies are outpacing both legislative and judicial responses. Thus far, legislatures hesitant to address the ethical uncertainties in IVF have been slow to adopt clear guidelines regarding the disposition of the frozen preem...

Energy balance is regulated by ghrelin that is a neuroendocrine modulator. Ghrelin is expressed in reproductive organs. However, the role of ghrelin during in vitro maturation and bovine preimplantational development is limited. The purpose of this study was to determine the expression of ghrelin (GHRL) and its receptor growth hormone secretagogue receptor 1A (GHS-R1A) mRNA expression, and cumu...

Acetamiprid (ACE) and imidacloprid (IMI) are two major members in the family of neonicotinoid pesticides, which are synthesized with a higher selectivity to insects. The present study determined and compared in vitro effects of ACE, IMI and nicotine on mammalian reproduction by using an integrated testing strategy for reproductive toxicology, which covered sperm quality, sperm penetration into ...

background: in vitro maturation (ivm) of oocytes is a promising technique to reduce the costs and avert the side-effects of gonadotropin stimulation for in vitro fertilization (ivf). the pregnancy rates from oocytes matured in vitro are much lower than those of in vivo stimulation cycles, indicating that optimization of ivm remains a challenge. objective: in this study, we investigated the effe...

Patients who undergo assisted reproductive technology, specifically in vitro fertilization (IVF), are at an increased risk of developing ectopic pregnancy. 90% successfully treated with either single dose or multi-dose methotrexate intervention.

We present an uncommon case of ectopic pregnancy following In-vitro fertilization in a 32 year old infertile Banker who, prior to IVF treatment, was diagnosed with stage 4 endometriosis by laparoscopy. She presented after 4 years of being unable to conceive with associated severely painful menstrual periods and deep dyspareunia. She had In-vitro fertilization and embryo transfer of two Day 3 em...

  Purpose: Estrogen as a crucial hormone during pregnancy acts by two types of receptors.   Estrogen receptor alpha, expressed by estrogen receptor 1 (ESR1) gene, is more abundant and   exists in all human reproductive systems. Association of ESR1 gene polymorphism has been   shown in some reproductive fields such as spontaneous abortion, endometriosis-related infertility   and in vitro fertili...

The aim of this study was to find the factors explaining the probability of success of in-vitro fertilization (IVF)-embryo transfer and its different stages: stimulation, fertilization and implantation. The sample came from a retrospective cohort followed in the IVF-embryo transfer centre of the Centre Hospitalier Universitaire of Pellegrin, Bordeaux, France; the data from 471 couples giving ri...