According to the 2010 WHO classification of digestive system tumors, esophageal low‐grade intraepithelial neoplasia (LGIEN) is associated with ultrastructural and cytological abnormalities confined to the lower half of the epithelium, and squamous cell carcinoma (SCC) is defined as tumor invasion of the lamina propria or penetration into deeper tissue layers. We here reported a rare esophageal ...

Heat shock protein (HSP) is thought to play important roles in the cell cycle and various process of carcinogenesis. This study was performed to evaluate the expression of heat shock protein (HSP70) and estrogen receptor (ER) and Ki-67 and to assess relationship between them in cervical squamous cell neoplasia. The materials were 50 cervical squamous cell lesions, consisted of 30 cervical intra...

zinc has an important role in skin health and its deficiency reduces immunity. to evaluate levels of zinc in squamous cell carcinoma (scc) and basal cell carcinoma (bcc) of skin, we studied 44 bcc and 38 scc cases together with 33 controls. blood samples were taken and after separation of serum, levels of zinc, albumin and total protein were measured by atomic absorption, albumin kit and reflec...

Cutaneous squamous cell carcinoma (cSCC) is the second most common human cancer with over 250,000 new cases annually in the US and is second in incidence only to basal cell carcinoma. cSCC typically manifests as a spectrum of progressively advanced malignancies, ranging from a precursor actinic keratosis (AK) to squamous cell carcinoma (SCC) in situ (SCCIS), invasive cSCC, and finally metastati...

Received July 2009 Accepted January 2010 INTRODUCTION Renal pelvis is normally lined by urothelium and contains neither squamous nor intestinal epithelium. However, transitional cell epithelium undergoes phenotypic changes usually in the form of squamous metaplasia.(1) We report a rare case of intestinal metaplasia of the renal pelvis with cytokeratin profile and assessment of the tumor markers...

Background & Objective: Laryngeal squamous cell carcinoma (LSCC) is considered to be one of the most common cancers of the head and neck, accounting for roughly 90% of all malignant tumors of the larynx. To have a timely diagnosis for a better and practical therapy, molecular markers have to be investigated. The aim of this study was to determine the expression of Cyclin D1 (CD...

A squamous cell carcinoma in situ (corneal intraepithelial neoplasia) was diagnosed in the right eye of an 11-year-old female Golden Retriever. Papillomavirus antigen was not detected in the excised tissues, and the tumor was suspected to be a sequel to previous injury. The tumor was removed by lamellar keratectomy, and the surgical bed was subjected to double freeze-thaw cryotherapy. Tumor reg...

Synchronous second primary tumors (SPTs), especially esophageal squamous cell neoplasia (ESCN), in patients with head and neck squamous cell carcinoma (HNSCC) are not uncommon. Image-enhanced endoscopy (IEE) screening may identify SPTs while there is no evidence to support its benefit. We prospectively recruited an adult cohort with newly-diagnosed HNSCC for IEE screening of upper gastrointesti...