Determining the middle of the bacteria cell and the proper placement of the septum is essential to the division of the bacterial cell. In E. coli, this process depends on the proteins MinC, MinD, and MinE. Here, the Lattice Boltzmann method (LBM) is used to study the dynamics of the oscillations of the min proteins from pole to pole. This determines the midcell division plane at the cellular le...

One of the most debilitating effects of primary aging is the decline in aerobic exercise capacity. One of its causes is an age-related decline in peak exercise stroke volume. This study's main purpose was to determine the cardiovascular adaptations to aging that most influence peak exercise stroke volume in the elderly. We hypothesized that increased left ventricular (LV) filling and mild conce...

PURPOSE sarcopenia plays a principal role in the pathogenesis of frailty and functional impairment that occur with aging. There are few published accounts that examine the overall benefit of resistance exercise (RE) for lean body mass (LBM) while considering a continuum of dosage schemes and/or age ranges. Therefore, the purpose of this meta-analysis was to determine the effects of RE on LBM in...

The purpose of this study was to determine the best scaling method to account for the effects of body size on measurements of overall cardiac function and subsequently the interpretation of data based on cardiac power output (CPO). CPO was measured at rest (CPO(rest)) and at maximal exercise (CPO(max)) on 88 and 103 healthy but untrained men and women, respectively, over the age range of 20-70 ...

A new immersed boundary-lattice Boltzmann method (IB-LBM) is proposed and validated in this work by its application to simulate incompressible viscous flows. The conventional IB-LBM based on the lattice Boltzmann equation with external forcing term, which contains a boundary velocity to represent the effect that the moving boundary exerts on the bounce-back distribution functions, whereas the p...

We present a novel approach at simulating fluids in real-time by coupling the Lattice Boltzmann Method for Shallow Waters (LBMSW) with particle systems. The LBM can handle arbitrary underlying terrain and arbitrary fluid depth, which, in turn, allows us to extend it to track dry regions. The LBM is also two-way coupled with rigid bodies. The particle system adds more detail to the LBM; breaking...

Protein-depleted states generate allosteric inhibition of liver cystathionine β-synthase (CBS), which governs the first enzymatic step of the transsulfuration cascade, resulting in upstream accretion of homocysteine (Hcy) in body fluids. A similar Hcy increase may arise from normal hepatocytes undergoing experimentally-induced impairment of betaine-homocysteine methyltransferase (BHTM) activity...

The lattice Boltzmann method (LBM) has evolved to a promising alternative to the well-established methods based on finite elements/volumes for computational fluid dynamics simulations. Ease of implementation, extensibility, and computational efficiency are the major reasons for LBM’s growing field of application and increasing popularity. In this paper we give a brief introduction to the involv...

INTRODUCTION Patients with systemic lupus erythematosus (SLE) are at an increased risk of developing low bone mass (LBM) or osteoporosis, either because of the disease itself or due to its treatment. Osteoporosis and osteoporotic fractures significantly contribute to morbidity and mortality. We aimed to determine the associations of bone mineral density (BMD) changes with the duration of SLE, a...