Lime witches’ broom phytoplasma (16SrII, LWB) causes major losses to lime cultivation in Iran. The role of its immunodominant membrane protein (IMP) in the specific interaction with vector proteins was addressed. The carboxy terminal moiety of LWB IMP, coding the extracellular part of the protein, was expressed (LWB f∆IMP) as a tool to study IMP interactions with insect proteins. In preliminary...

The interactive and multi-protagonist (IMP) film is a novel concept that extends the hypermovie genre. The IMP film is based on the common structures of linear narrative storytelling and provides the viewer with various decision points within the evolving story that support an active choice among different protagonists’ views. The viewer will thus be elevated to the role of a decision maker. Th...

INTRODUCTION (123)I-N-isopropyl-p-iodoamphetamine ((123)I-IMP) is metabolized and converted to (123)I-p-iodoamphetamine ((123)I-PIA) by CYP2C19 in humans. Since variations in (123)I-PIA levels reflect variations in CYP2C19 activity, CYP2C19 activity can be estimated by quantitative analysis of (123)I-PIA levels. Thus, (123)I-IMP administration can provide diagnostic information not only regardi...

The catalytic activity of carbamoyl phosphate synthetase (CPS) from Escherichia coli is allosterically regulated by UMP, IMP, and ornithine. Thirteen amino acids within the domain that harbors the overlapping binding sites for IMP and UMP were mutated to alanine and characterized. The four residues that interact directly with the phosphate moiety of IMP in the X-ray crystal structure (K954, T97...

Inosine 5'-monophosphate dehydrogenase (IMP-DH) activities were measured in human lymphocytes (exhibiting type I IMP-DH activity) and human lymphoblasts (exhibiting type II IMP-DH activity) in the presence of various amounts of mycophenolic acid (MPA) (0-20 mumol/L) and MPA glucuronide (MPAG) (0-200 mumol/L). Moreover, the influences of human serum albumin (HSA) and human plasma on the MPA- and...

Fast protein and metabolite liquid chromatography (FPLMC) was introduced years ago to enable the easy separation of high-molecular compounds such as proteins from small molecules identification low-molecular substances. In this paper, method is applied for rapid evaluation freshness monitoring aging animal meat fish. A novel chromatographic sensor developed with a deep UV LED-based photometric ...

Cardiac output was determined by impedance cardiography (Q(imp)) and a rebreathing method (Q(reb)) during exercise of loads up to 90 W. The correlation between Q(imp) and Q(reb) was generally good, but it was found in two of four subjects that Q(imp) was slightly lower than Q(reb) at the higher exercise levels. The regression equation for both Q values was: Q(imp) = 0.91 Q(reb) + 0.25 (l/min, r...

1Servizio di Radiologia Vascolare ed Intervenistica 2Servizio di Nefrologia e Dialisi Azienda Ospedaliera «S. Camillo Forlanini» Roma. Pervenuto alla Redazione il 29.7.2002; revisionato il 27.8.2002; restituito corretto il 30.1.2003; accettato per la pubblicazione il 4.2.2003. Indirizzo per la richiesta di estratti: Dott. S. Pieri Via F. Algarotti, 8 Roma RM 00137 Tel. 06/86896690 Fax. 06/82768...

BACKGROUND Integrated molecular pathology (IMP) approaches based on DNA mutational profiling accurately determine pancreatic cyst malignancy risk in patients lacking definitive diagnoses following endoscopic ultrasound imaging with fine-needle aspiration of fluid for cytology. In such cases, IMP 'low-risk' and 'high-risk' diagnoses reliably predict benign and malignant disease, respectively, an...

OBJECTIVES The objective of this study was to characterize a novel IMP-type metallo-β-lactamase (MBL) found in an MDR clinical isolate of Pseudomonas aeruginosa. METHODS The P. aeruginosa isolate NRZ-00156 was recovered from an inguinal swab from a patient hospitalized in Western Germany and showed high MICs of carbapenems. MBL production was analysed by Etest for MBLs, an EDTA combined disc ...