A couple of [c2]daisy chains have been assembled in each case from four components in quantitative yields at room temperature in acetonitrile as a result of the self-templated clippings of their [24]crown-8 rings by reversible imine bond formation around secondary dialkylammonium recognition sites in their stalks.

The development of one-pot imine formation and asymmetric Pictet-Spengler reactions cocatalyzed by a chiral thiourea and benzoic acid is described. Optically active tetrahydro-beta-carbolines, ubiquitous structural motifs in biologically active natural products, are obtained in high ee directly from tryptamine and aldehyde precursors.

The nitrile imine-mediated tetrazole–ene cycloaddition is a widely used class of photoligation. Optimizing the reaction outcome requires detailed knowledge tetrazole photoactivation profile, which can only partially be ascertained from absorption spectroscopy, or otherwise involves laborious monitoring in solution. Photodissociation action spectroscopy (PDAS) combines advantages optical and mas...

Mesoporous carbon derived from natural vitamin B12 is applied for the first time in organic synthesis and exhibits exceptionally high dual activity for imine formation via the cross-coupling of alcohols with amines and the self-coupling of primary amines using molecular oxygen or air as the terminal oxidant.

Manganese dioxide is employed as an in situ oxidant for the one-pot conversion of alcohols into imines. In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation-imine formation-reduction sequence is reported. This procedure enables alcohols to be converted directly into both secondary and tertiary amines.

The title Schiff base, C(17)H(19)IN(2)O, is not planar, displaying a dihedral angle of 34.9 (2)° between the two aromatic rings. The mol-ecular conformation allows the formation of a strong intra-molecular O-H⋯N hydrogen bond with graph-set motif S(6) between the hy-droxy group and the imine N atom.

The title compound, C(19)H(24)N(2)O(2), adopts the phenol-imine tautomeric form. An intra-molecular O-H⋯N hydrogen bond results in the formation of a six-membered ring. The aromatic rings are oriented at a dihedral angle of 17.33 (16)°. Inter-molecular C-H⋯π inter-actions occur in the crystal.

A morphological transformation from hybrid micelles to giant vesicles was observed in aqueous dispersion associated with formation of a double-chained amphiphile as a result of the migration of dodecylamine from the amphiphilic imine to the amphiphilic aldehyde within the hydrophobic environment of amphiphilic aggregates.