نتایج جستجو برای: il 22

تعداد نتایج: 347112  

Journal: :Journal of immunology 2010
Spencer C Liang Cheryl Nickerson-Nutter Debra D Pittman Yijun Carrier Debra G Goodwin Kathleen M Shields Andre-Jean Lambert Scott H Schelling Quintus G Medley Hak-Ling Ma Mary Collins Kyriaki Dunussi-Joannopoulos Lynette A Fouser

IL-22 is made by a unique set of innate and adaptive immune cells, including the recently identified noncytolytic NK, lymphoid tissue-inducer, Th17, and Th22 cells. The direct effects of IL-22 are restricted to nonhematopoietic cells, its receptor expressed on the surface of only epithelial cells and some fibroblasts in various organs, including parenchymal tissue of the gut, lung, skin, and li...

Journal: :International journal of clinical and experimental pathology 2014
Qing Wang Li Wang Jun Shao Yan Wang Li-Ping Jin Da-Jin Li Ming-Qing Li

It has reported that interleukin-22 (IL-22) promotes the invasion of tumor cells. IL-22 in the endometriotic milieu stimulates the proliferation of human endometrial stromal cells (ESCs). The present study aimed to elucidate whether and how IL-22 regulates the invasion of ESCs from adenomyosis. The expression of IL-22 and its receptors in normal endometrium, eutopic endometrium and ectopic lesi...

Journal: :Infection and immunity 2007
Georg F Weber Sylvia Schlautkötter Simone Kaiser-Moore Felicitas Altmayr Bernhard Holzmann Heike Weighardt

Interleukin-22 (IL-22) is a recently discovered proinflammatory cytokine, structurally related to IL-10. Since IL-22 is induced by lipopolysaccharide in vivo, we studied the role of IL-22 in a model of polymicrobial peritonitis. Quantitative real-time reverse transcription-PCR analysis showed marked induction of IL-22 and IL-22 receptor in spleen and kidney during the course of sepsis. The biol...

Journal: :Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013
Sebastian Kobold Stefanie Völk Till Clauditz Natascha Jennifer Küpper Sarah Minner Amanda Tufman Peter Düwell Michael Lindner Ina Koch Simon Heidegger Simon Rothenfuer Max Schnurr Rudolf Maria Huber Waldemar Wilczak Stefan Endres

INTRODUCTION In lung cancer, interleukin-22 (IL-22) expression within primary tissue has been demonstrated, but the frequency and the functional consequence of IL-22 signaling have not been addressed. This study aims at analyzing the cellular effects of IL-22 on lung carcinoma cell lines and the prognostic impact of IL-22 tissue expression in lung cancer patients. METHODS Biological effects o...

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