Histamine is a critical mediator if itch in urticaria, however, many patients with chronic spontaneous urticaria (CSU) spite of treatment antihistamines. Further, it widely known that the CSU, over time can lose clinical responses to antihistamines as well. We hypothesized limitation these therapies partially due other immune mediators amplifying histaminergic pathway. focused specifically on I...

Today, the use of oak as a replacement feed in poultry diets is well documented. However, oak contains polyphenol compounds (tannins) as antinutrient factors resulted in limited usage in the poultry rations. Generally, consumption of feeds containing tannin could affect gene expression level of immune system. Therefore, the aim of this study was to investigate the effect of different levels of ...