Objective: To evaluate the frequency of autoantibodies (Ab) against 21 hydroxylase (21OH), side-chain cleavage (SCC) and 17a-hydroxylase (17OH), in Addison’s disease (AD) and autoimmune polyendocrine syndrome type III (APSIII). Design and Methods: We used radiobinding assays and in vitro translated recombinant human S-21OH, S-SCC or S-17OH and studied serum samples from 29 AD (18 idiopathic, 11...

Abstract Canine visceral leishmaniasis (CVL) caused by Leishmania (Leishmania) infantum is transmitted phlebotomine sandflies and a major zoonotic disease in Brazil. Due to the southward expansion of within country central role dogs as urban reservoirs parasite, we have investigated occurrence CVL two municipalities Erval Velho Herval d’Oeste Midwest region Santa Catarina state. Peripheral bloo...

Aim: To determine the rate of malignancy in complex renal cystic lesions. Material and methods: We studied 111 patients both male female above age 18 years with lesions classified as Bosniak category IIF, III, IV on CT. Patients categories I II were excluded from study. The was analyzed. Results: mean 47.58±15.05 years. 27% 29.7% III 43.2% IV. overall 62.2% all who presented IIF,III 33.3%, 54.5...

Abstract Introduction: In patients with autoimmune skin blistering diseases (ABDs), the diagnostic gold standard has classically been direct and indirect immunofluorescence (DIF and IIF), despite inherent technical problems of autofluorescence. Aim: We sought to overcome autofluorescence issues and compare the reliability of immunofluorescence versus immunohistochemistry (IHC) staining in the d...

OBJECTIVES Recently published findings suggested that antineutrophil cytoplasmic antibodies (ANCA), particularly those with a cytoplasmic (C-ANCA) labelling pattern and targeting proteinase 3 (anti-PR3), might be markers of tuberculosis (TB). This is a critical issue, because C-ANCA/anti-PR3 were considered to be a highly specific hallmark of Wegener's granulomatosis or microscopic polyangiitis...

A series of 1-phenyl-3-(2-{substituted-phenylhydrazono})-indolin-2-one derivatives (IIa-k) were synthesized. The compounds were evaluated for their anti-inflammatory, analgesic, ulcerogenic and antimicrobial actions. Among the tested compounds, two compounds IIf and IIk showed higher degree of anti-inflammatory activity (>75% activity of standard indomethacin). These compounds were further test...

Existfen buffer allocat,ion ~nrt.lmrls IISC\ prcca.lculnt,ed para.met,ers t,o nlake I>ufT~r allocation decisions. The main idpa proposed here is to design an ndnp!nhlc hufi’er alloca.lion algorithm that, will aut,onlatically optimize itself for t,he specifir query workload. To achievtt,his adapt.nhili(,y. wf‘ propose IISing rnn-l.ilnc? inforniiiLion, 511c.11 its 1 Iif> loved of t.hc syshn, in o...

How neurons in the cerebral cortex process and transmit information is a long-standing question in systems neuroscience. To analyze neuronal activity from an information-energy efficiency standpoint, Berger and Levy calculated the maximum Shannon mutual information transfer per unit of energy expenditure of an idealized integrateand-fire (IIF) neuron whose excitatory synapses all have the same ...

The main objective of this work was to optimize the serum free, DMSO free cryopreservation protocol for adipose derived adult stem cells (ASCs), suspended in polyvinylpyrrolidone (PVP) solution, which would help to avoid intracellular ice formation (IIF) – a well known cause of cell death during cryopreservation [1]. Passage 1 (P1) ASCs were cultured in our lab, washed and suspended in a 10% w/...

This paper presents an efficient parallel information retrieval (IR) system which provides fast information service for the Internet users on lowcost high-performance PC-NOW environment. The IR system is implemented on a PC cluster based on the Scalable Coherent Interface (SCI), a powerful interconnecting mechanism for both shared memory models and message passing models. In the IR system, the ...