The Brazilian Ministry of Health recommends the performance of serological tests in patients with clinical signs of Sexually Transmitted Diseases. However, data are lacking to affirm the necessity of testing these patients for human T-lymphotropic virus type 1 or type 2. This is a cross-sectional study with 120 patients seen at the Sexually Transmitted Diseases unit of the Sanitary Dermatology ...

The discovery of lymphoid B-Iymphotropic herpesvirus-producing cell lines from M. arctoides peripheral lymphocytes (MAL-l) producing their own lymphotropic virus HVMA was reported earlier [1]. Subsequently, two more M. arctoides virus-producing lymphoid cell lines (MAL-2, MAL-3) were discovered in our laboratory. The cells of some baboon lymphoid cultures, parallel with B-Iymphotropic herpesvir...

Background: Human T-cell lymphotropic viruses 1 (HTLV1) is endemic in specific regions. We aimed to determine the prevalence of HTLV I infection among blood donors in southeast Iran.   Methods: This cross-sectional study was conducted between April 2005 and March 2015. Sera were collected from blood donors and were tested for the presence of HTLV1 specific antibody using ELISA. Reactive sample...

Adult T-cell lymphoma (ATL) is a hematological malignancy of CD4+ mature T-lymphocytes commonly associated with chronic human T-lymphotropic virus type I (HTLV-1) infection. Chronic HTLV-1 infection induces oncogenic mutations in T-cells, leading to an acute malignant transformation host cells. Atypically, ATL presents dermatological and pulmonary symptoms consistent “smoldering” disease patter...

After the addition of human T-cell lymphotropic virus type I (HTLV-I)-infected lymphocytes to enterocyte monolayers, the lymphocytes adhered via microvilli from both cell types and shed virus onto the enterocyte surface. Virus fused with the epithelial membrane and infected these cells as confirmed by electron microscopic immunocytochemistry, in situ hybridization, and amplification by polymera...