Viral immediate-early (IE) genes are the first class of viral genes expressed during primary infection or reactivation from latency. They usually encode regulatory proteins that play crucial roles in viral life cycle. In a previous study, four regions in the KSHV genome were found to be actively transcribed in the immediate-early stage of viral reactivation in primary effusion lymphoma cells. T...

The protistan parasite Mikrocytos mackini, the causative agent of Denman Island disease in the oyster Crassostrea gigas in British Columbia, Canada, is of wide concern because it can infect other oyster species and because its life cycle, mode of transmission, and origins are unknown. PCR and fluorescent in situ hybridization (FISH) assays were developed for M. mackini, the PCR assay was valida...

background: the occurrence and the mortality related to breast cancer (bc) in iranian female population has increased over time. although there are many studies on bc and related risk factors, however, the epidemiological aspects of this melanoma in iranian females are uncertain. therefore, the aim of this study was to determine the relationship between demographical and clinical factors on the...

Tanzania continues to enjoy stability and growth in different sectors similar to other countries; however, some challenges persist in the health sector, especially in the area of cancer care. The current study aimed at reviewing social economic status (SES), as well as factors contributing to the increased burden of breast cancer (BC) in Tanzania. The current study reviewed different articles a...

A BC-tree (block-cutpoint-tree) is a tree (with at least two vertices) where the distance between any two leaves is even. Motivated from the study of the “core” of a graph, BC-trees provide an interesting class of trees. We consider questions related to BC-trees as an effort to make modest progress towards the understanding of this concept. Constructive algorithms are provided for BC-trees with...

Skeletal muscle exhibits a loss of muscle mass and function with age. Decreased regenerative potential of muscle stem/progenitor cells is a major underlying cause of sarcopenia. We analyzed microRNAs (miRNA) that are differentially expressed in young and old myoblasts, to identify novel intrinsic factors that play a degenerative role in aged skeletal muscle. miR-431, one of decreasing miRNAs in...

A reinvestigation of a Fijian collection of Cacospongia mycofijiensis has yielded the known mycothiazole and a novel heterocyclic, CTP-431 (1). Its structure including absolute configuration as 8R,9R,10S,13S was established using NMR data, calculated DFT (13)C chemical shifts and results from X-ray crystallography. It is possible that the tricyclic skeleton of CTP-431 (1) is biosynthetically re...

The problem of ricochet of any projectile when it fails to hit the target or ifter its impact on the target, is of great importawe for the services as well as for the police personnel. The ricochet process is of constant concern for the Airforce authorities also during air to ground attack, due to the chances of hit to own a h a & from own fire. Whenever any bullet hits the pound short of targe...