Survivin is a member of the inhibitor of apoptosis protein family (IAP) that acts in both inhibition of apoptosis and regulation of the cell cycle. Despite the fact that survivin is overexpressed in almost all human malignancies, its expression is undetectable in most normal adult tissues, which is what makes it a potential target for anticancer interventions. The aim of this work was to invest...

inflammation can lead to malabsorption of important micronutrients such as iron. malabsorption and nutritional deficiency can be caused by a variety of pathological and environmental factors causing a range of other symptoms commonly caused by both h. pylori infection and coeliac disease (cd). national guidelines suggest the routine taking of duodenal biopsies to exclude cd when investigating p...

Iron deficiency anemia (IDA) is the most common nutritional anemia and considered a major public health problem worldwide. This cross-sectional study was carried out to investigate the prevalence and risk factors of IDA among 187 children aged below 15 years from rural areas in Yemen. Clinical data was collected by measuring hemoglobin level (Hb), serum iron (SI), serum ferritin (SF), and total...

Information Dispersal Algorithms (IDAs) have been widely applied to reliable and secure storage and transmission of data files in distributed systems. An IDA is a method that encodes a file F of size L = |F | into n unrecognizable pieces F1, F2, · · · , Fn, each of size L/m (m < n), so that the original file F can be reconstructed from any m pieces. The core of an IDA is the adopted non-systema...

High-accuracy optimization is the key component of time-sensitive applications in computer sciences such as machine learning, and we develop single-GPU Iterative Discrete Approximation Monte Carlo Optimization (IDAMCS) and multi-GPU IDA-MCS in our previous research. However, because of the memory capability constrain of GPUs in a workstation, single-GPU IDA-MCS and multiGPU IDA-MCS may be in lo...

BACKGROUND Hepcidin, a key regulator of iron homeostasis, is increased in response to inflammation and some infections, but the in vivo role of hepcidin, particularly in children with iron deficiency anemia (IDA) is unclear. We investigated the relationships between hepcidin, cytokines and iron status in a pediatric population with a high prevalence of both anemia and co-morbid infections. ME...

BACKGROUND A maximum likelihood method of mixed distribution analysis (MDA) is presented as a method to estimate the prevalence of iron deficiency anaemia (IDA) in Costa Rican infants 12-23 months old. MDA characterizes the parameters of the admixed distributions of iron deficient anaemics and non-iron-deficient-anaemics (NA) from the frequency distribution of haemoglobin concentration of the t...