Intracranial pressure (ICP) monitoring and management have substantially improved the outcome of patients with traumatic brain injury (TBI). However, rapid elevations in ICP remain a significant problem as they may lead to secondary brain injury and worse outcome due to cerebral ischemia. Current therapy is targeted towards treating rapid ICP elevations after they occur. Ideally, anticipatory t...

BACKGROUND Monitoring of intracranial pressure (ICP) is highly important for detecting abnormal brain conditions such as intracranial hemorrhage, cerebral edema, or brain tumor. Until now, the monitoring of ICP requires an invasive method which has many disadvantages including the risk of infections, hemorrhage, or brain herniation. Therefore, many non-invasive methods have been proposed for es...

BACKGROUND The Brain Trauma Foundation (BTF) guidelines published in 2007 suggest some indications for intracranial pressure (ICP) monitoring in severe traumatic brain injury (TBI). However, some studies had not shown clinical benefit in patients with severe TBI; several studies had even reported that ICP monitoring was associated with an increased mortality rate. The effect of ICP monitoring h...

The physiological effect of posture on intracranial pressure (ICP) is not well described. This study defined and evaluated three mathematical models describing the postural effects on ICP, designed to predict ICP at different head-up tilt angles from the supine ICP value. Model I was based on a hydrostatic indifference point for the cerebrospinal fluid (CSF) system, i.e., the existence of a poi...

Following recent studies, the automatic analysis of intracranial pressure pulses (ICP) seems to be a promising tool for forecasting critical intracranial and cerebrovascular pathophysiological variations during the management of many neurological disorders. MOCAIP algorithm has recently been developed to automatically extract ICP morphological features. The algorithm is able to enhance the qual...

The authors correlated the computed tomographic (CT) findings and intracranial pressure (ICP) in 150 consecutive comatose head injury patients to determine if noninvasive CT can help identify the patients not requiring ICP monitoring. The study reveals that a majority of patients (55%) with hemorrhagic lesions shown by CT suffer from intracranial hypertension and require ICP monitoring for prop...

Purpose The purpose of this study was to determine if there is a quantitative relationship between chronic intracranial pressure (ICP) and peripapillary Bruch's membrane (pp-BM) shape and to determine whether change in pp-BM shape can be detected within 1 hour after ICP lowering by lumbar puncture (LP). Methods In this study, 30° nasal-temporal optical coherence tomography B-scans were obtain...

Chronic communicating hydrocephalus is a significant health problem affecting up to 20% of survivors of spontaneous subarachnoid hemorrhage (SAH). The development of new treatment strategies is hampered by the lack of well characterized disease models. This study investigated the incidence of chronic hydrocephalus by evaluating the temporal profile of intracranial pressure (ICP) elevation after...

In children with craniosynostosis, raised intracranial pressure (ICP) and upper airway obstruction (UAO) are both common features. However, potential interactions between UAO and ICP during sleep are poorly understood. The aim of the present study was to compare the levels of ICP during sleep between a group of patients with syndromic craniosynostosis (with facial involvement and consequent UAO...

In this paper we combine the Iterative Closest Point (’ICP’) and ‘point-to-plane ICP‘ algorithms into a single probabilistic framework. We then use this framework to model locally planar surface structure from both scans instead of just the ”model” scan as is typically done with the point-to-plane method. This can be thought of as ‘plane-to-plane’. The new approach is tested with both simulated...