CONTEXT There are contradictory results on the effect of hypothyroidism on the changes in hemostasis. Inadequate population-based studies limited their clinical implications, mainly on the risk of venous thromboembolism (VTE). This paper reviews the studies on laboratory and population-based findings regarding hemostatic changes and risk of VTE in hypothyroidism and autoimmune thyroid disorders...

Hypothyroidism is the most common endocrine disorder in dogs. The present paper puts on record various ailments associated with primary hypothyroidism caused by thyroxine (T4) deficiency and peripheral disorders in euthyroid dogs, which mimic hypothyroidism. The study undertaken on 10,172 dogs presented at the clinics with skin and coat incongruity, revealed clinical manifestations suggestive o...

Congenital hypothyroidism is a preventable cause of mental retardation. Since clinical signs of congenital hypothyroidism do not generally become obvious before three months of age, screening programmes have been introduced in North America and Europe, which consist of T4 or TSH screening on newborn infants on the third day of life. The screening for congenital hypothyroidism was initiated in P...

Hypothyroidism is one of the most common disorders encountered in an endocrine office practice. This article reviews the epidemiology, etiology, clinical presentation, diagnosis, and treatment of hypothyroidism. We emphasize some of the more recent issues, such as combination thyroid hormone therapy, management of hypothyroidism during pregnancy, and the management of subclinical hypothyroidism.

Hypothyroidism is a common disorder in women in their reproductive age. The present study shows that the prevalence of hypothyroidism is 9% in pregnant women. The study also reveals that of hypothyroidism are adequately treated and monitored good maternal and fetal outcome results. Evidence from the present study supports the need for screening of hypothyroidism in pregnancy.

Hypothyroidism can cause a variety of signs and symptoms of the neuromuscular system. However, ptosis in a patient with hypothyroidism is very rare. We report here on a case of central hypothyroidism that was due to Sheehan's syndrome and it manifested as bilateral ptosis in a 51-yr-old woman. She complained of exertional dyspnea and weakness. About 25-yr ago, she had a history of severe postpa...

BACKGROUND Sub-clinical hypothyroidism (SCO) poses diagnostic and management difficulties for pathologists and clinicians. Cases of SCO are now diagnosed with increasing frequencies worldwide mainly because of availability of more sensitive methods for serum TSH, total T3 and free T4 assays. The rate of progression of SCO to overt hypothyroidism varies in different populations. Sub-clinical hyp...

BACKGROUND There is an increased prevalence of hypothyroidism in chronic kidney disease (CKD) patients as the glomerular filtration rate falls. However, there is a paucity of Indian data in this respect. METHODS A cross-sectional analysis was performed based on the database of the information system of a tertiary care hospital in northern India to retrieve results of nephrology CKD outpatient...

Cardiac diseases, especially chronic heart failure which, according to the World Health Organization, affects 1.5-2% of global population, are number one cause mortality and morbidity worldwide, including Ukraine. Chronic is often accompanied by endocrine disorders, hypothyroidism, diagnosis which has increased over past 10 years, facilitates rapid progression due reduced metabolic processes al...

Background & Aims: Since at early pregnancy (<20 week) fetal thyroid gland is undeveloped, normal development of the Fetal brain is highly dependent on maternal thyroid hormones. There are excessive adverse perinatal outcomes associated with overt and subclinical hypothyroidism such as increase of Abortion, preeclampsia, placenta Abruption, LBW, preterm labor, impaired fetal neuropsychological ...