Skeletal, renal, and intestinal effects of VX-2 carcinoma in rabbits were studied in relation to the pathogenesis of a hypercalcemic and hypophosphatemic state induced by the tumor. On the basis of an initial screening, alkaline phosphatase was chosen as a biochemical marker for monitoring any change in the cellular activity of bone, kidney, intestine, and liver in the carcinoma-bearing rabbits...