By JOHN E. LUCAS, M.D. AND ALBERT B. HAGEDORN, M.D. T HE ORAL USE of iroms ins tise treatmemst of irons deficienicv ansemia has heens well established! amid documensted. However, the paremsteral use of this metal ins the treatment of hypochromic ansemia dine to irons demmcienscy has, ins the past-, been limited by the inscidemsce of toxic reactionss si-hems ansy hut suboptimal doses of the prep...

The red cell distribution width (RDW) is an index of the variation in red cells size (anisocytosis). A study was conducted to examine the validity of using RDW in improving classification of microcytic anaemias. A total of 300 blood samples collected from a patient population aged 3 months to 55 years who were referred for haemoglobin electrophoresis were examined at the Aga Khan University Hos...

Leucoderma syphiliticum (LS), originally described as syphilide pigmentaire, encompasses a spectrum of dyschromic lesions that emerge during the course of secondary syphilis. Very few case reports are available in modern biomedical databases. We present the case of a 57-year-old HIV-infected male patient who presented with several round to oval, non-scaling, slightly raised and well-demarcated ...

A genetic screen for mutations affecting embryogenesis in the medaka, Oryzias latipes, identified a mutant, whiteout (who), that exhibited hypochromic anemia. The who mutant initially had the normal number of blood cells, but it then gradually decreased during the embryonic and larval stages. The blood cells in the who mutants show an elongated morphology and little hemoglobin activity. Genetic...

Non-hemin iron content in gastric juice was examined in 46 patients with various blood diseases, especially idiopathic hypochromic anemia and in 26 healthy controls. 1. The iron content in gastric juice was found to be 290 μg/ dl in healthy controls, a lower value of 110 μg/ dl in idiopathic hypochromic anemia and a higher value of 550 μg / dl in aplastic anemia. These values were in a close co...

1Institut National de la Santé et de la Recherche Médicale (INSERM) Unité (U) 773, Centre de Recherche Biomédicale Bichat Beaujon CRB3, Paris; Université Paris 7 Denis Diderot; and Centre Français des Porphyries, Hôpital Louis Mourier, Colombes, France; 2Institut Pasteur, Unité de Génétique des Mammifères, Paris, France; Assistance Publique–Hôpitaux de Paris (AP-HP), Hôpital Bichat, 3Laboratoir...

MICROCYTIC hypochromic anemia induced by a diet deficient in pyridoxine is well documented in swine,’ monkeys,2 dogs,3 cats,4 ducks,5 and chicks.#{176}In man, pyridoxine deficiency anemia was first described in 1956 by Harris et al.;7 subsequently an increasing number of cases have been reported by others. In 1953, Synderman et al.8 produced pyridoxine deficiency in two infants with cerebral de...