Hypertrophic cardiomyopathy is a fascinating disease entity in which hypertrophy of the myocardium occurs, primarily as a result of mutations of genes encoding the cardiac sarcomere.1–3 Our knowledge of patients with this unique disease of the heart muscle has advanced significantly. Once thought to be a rare malignant disease with a high risk of sudden death, population studies have revealed h...

Sudden cardiac death in young athletes is an infrequent, but catastrophic event. Hypertrophic cardiomyopathy, coronary artery anomalies, and arrhythmias are common identifiable causes of sudden cardiac death. Many of these disorders can be difficult to diagnose, and athletes may be completely asymptomatic prior to their sudden death event. This article reviews causes of sudden cardiac death in ...

Abstract;
 Coronary artery anomalies are uncommon cardiac diseases. It is mostly detected incidentally in the adult population as well being usually asymptomatic. Although its prevalence low, association with atherosclerosis, arrhythmias, and hypertrophic cardiomyopathy important for sudden death. According to literature, of coronary anomaly rare. No case accompanied by absence left anteri...

leading cause of death throughout the industrialized nations of the world. Central to this statistic is our current inability to effectively repair or otherwise reverse severe forms of cardiac dysfunction and pathologic remodeling that characterizes a failing heart. In response to hypertension, ischemic disease, valvular insufficiency, viral myocarditis, and genetic mutations in sacomeric prote...

Sudden death was recorded by continuous ambulatory electrocardiographic (Holter) monitoring in a 62 year old man with hypertrophic cardiomyopathy and atrial fibrillation, who had been treated for four days with verapamil 360 mg orally. Analysis of the tape showed a third degree atrioventricular block followed by complete asystole. The sudden death could be related to treatment with verapamil.

BACKGROUND Transgenic mouse models expressing a missense mutation (R92Q) or a splice donor site mutation (trunc) in the cardiac troponin T (cTnT) model familial hypertrophic cardiomyopathy (FHC) in humans. Although males from these strains share the unusual property of having significantly smaller ventricles and cardiac myocytes, they differ with regard to systolic function, fibrosis, and gene ...

The objective of this study was to observe the acute cytotoxic effects of hematoporphyrin monomethyl ether sonodynamic therapy (HMME-SDT) on hypertrophic scar fibroblasts of rabbit ears. We first assessed the effects of different irradiation times and HMME concentrations on the survival of hypertrophic scar fibroblasts using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)...

Hypertrophic cardiomyopathy was first recognized from pathologic studies in 1958 (1) and subsequently analyzed in detail from hemodynamic (2), echocardiographic (3) and electrophysiologic standpoints (4). It is characterized by a hypertrophied heart with a nondilated left ventricular chamber in the absence of any illness that induces an increased myocardial mass. It is frequently associated wit...

Although faintness, syncope, and sudden death are common in hypertrophic obstructive cardiomyopathy, their cause has not been well documented. The occurrence of ventricular asystole causing syncope after exercise is described in one patient. The elucidation of the disturbance of rhythm may, therefore, be ofgreat importance, as sudden death may be avoided in these patients by the prophylactic us...

Introduction: Hypertrophic cardiomyopathy (HCM) belongs to the very heterogeneous group of cardiomyopathies. This study aimed myocardial perfusion abnormalities on scintigraphy and assess risk sudden death from ventricular arrhythmia in hereditary sarcomeric HCM. Patients Methods: is a retrospective prospective descriptive over 18 months (January 01, 2021, July 31, 2022) records patients with d...