The acute antihypertensive effect of a new long-acting oral angiotensin I-converting enzyme (ACE) inhibitor, enalapril maleate, was assessed in 20 hypertensive patients, of whom 14 had essential hypertension, 4 had renovascular hypertension, one had hypertension associated with chronic renal failure, and one had primary aldosteronism. Enalapril maleate significantly lowered the blood pressure i...

INTRODUCTION We investigated the association between echocardiographic (Echo) left ventricular mass (LVM) indexed to body surface area (LVM/BSA) or height(2.7) (LVM/H(2.7)) and electrocardiographic (ECG) variables in 546 Chinese hypertensives. METHODS The study group was stratified by gender and by BMI into obese (BMI > or =28 kg/m(2)), overweight (BMI > or =24 kg/m(2) and BMI <28 kg/m(2)), a...

The aim of the study was to investigate whether diverse clinical blood pressure phenotypes are associated with free leptin surrogates, as reflected by plasma leptin, human soluble leptin receptor, and their ratio (ie, free leptin index) in nonobese normoglycemic subjects. Three separate clinic blood pressure measurements and ambulatory blood pressure monitoring were implemented to divide 494 su...

Hypertension is common in the elderly. While it is possible to reduce blood pressure in this age group, the value of such treatment in terms of reduced mortality and morbidity is unknown. The effects of a prescribed regimen depends inter alia on compliance. Therefore, this variable must be taken into account in assessing drug treatment in the elderly hypertensive. In general, the elderly comply...

RUDY JOSÉ NODARI JUNIOR1, GABRIELA SARTORI1, GRACIELLE FIN2, FRANCESCO OMARINI3, GIANLUCA BIANCO3,6, GIUSEPPE MESSINA4,5,6, MARCELLO TRAINA4, ANTONIO PALMA4 1Universidade do Oeste de Santa Catarina Brazil 2Mestrado em Biociências e Saúde da Universidade do Oeste de Santa Catarina, Brazil 3Associazione internazionale di Rieducazione Neuroposturale Psicocorporea, Italy 4Department of Psychologica...

INTRODUCTION Left ventricular geometry is associated with cardiovascular events and prognosis. The Tei index of myocardial performance is a combined index of systolic and diastolic dysfunction and has been shown to be a predictor of cardiovascular outcome in heart diseases. The relationship between the Tei index and left ventricular geometry has not been well studied. This study examined the as...

BACKGROUND People with hypertension display an inflammatory pattern that includes increased plasma concentrations of monocyte chemoattractant protein 1 (MCP-1) and C-reactive protein (CRP) and enhanced expression of tissue factor (TF) mRNA in blood monocytes. METHODS In this study, we investigated the relationship between CRP concentrations and TF and MCP-1 mRNA expression in unstimulated and...

Previous reports suggest that neuronal norepinephrine (NE) reuptake may be impaired in essential hypertension, perhaps because of dysfunction of the NE transporter, although the evidence is inconclusive. To further test this proposition, we applied phenotypically relevant radiotracer methodology, infusion of tritiated NE and quantification of NE metabolites, to 34 healthy lean subjects (body ma...