Background: Acne vulgaris is the most common condition encountered in dermatologic practice. Recent literature suggests racial and ethnic difference in the sequelae of acne complications with post acne hyperpigmentation topping the list. Therapeutic goals include promoting degradation of melanosomes and inhibiting their formation. Thus it is a challenge to treat patients of darker skin and find...

In developing countries like India, nutritional deficiencies are prevalent and hyperpigmentation due to protein energy malnutrition, zinc deficiency and pellagra are common. Indian women, especially vegetarian are prone to vitamin B12 deficiency. Vitamin B12 deficiency can present as anaemia, neurological defect, gastrointestinal symptoms or dementia. Hyperpigmentation as the first presentation...

abstract fixed drug eruption (fde) is a unique type of cutaneous drug reaction that typically recurs in the identical locations on re-exposure to the attributed drug. fde is characterized by the appearance of a single or multiple sharply demarcated violaceous erythematous plaques which heal with residual hyperpigmentation. a 27-year-old woman presented with multiple dark patches over her eyelid...