An infant is described who presented with ptosis and periorbital oedema and was found to have infantile cortical hyperostosis with thrombocytosis, raised IgM, and vitamin E deficiency.

Fig. 2 A 41-year-old man who suffered from pain in several joints for more than 10 years was referred for a bone scintigraphy. The patient was treated with non-steroidal anti-inflammatory drugs, but this treatment regimen did not result in a reduction of symptoms. Upon completion of the physical examination, no remarkable findings were noted. All routine laboratory tests were normal. The images...

This paper is a case report and literature review. The objective of this article is to address a rather unusual case of central cord syndrome in a patient with diffuse idiopathic skeletal hyperostosis and focal ossification of the posterior longitudinal ligament. We also discuss the mechanism of injury in central cord syndrome, as well as that specific to involvement of diffuse idiopathic skele...

Sternocostoclavicular hyperostosis (SCCH) is an ill-recognized, rarely diagnosed disease. Today, SCCH is widely considered part of the synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome. SCCH develops over years with intermittent attacks of pain, swelling, and reddening of the sternocostoclavicular region. The disease causes progressive hyperostosis, fusion of the sternocos...

In 1987, Chamot et al attempted to unify the various descriptions of osteoarticular disease associated with skin manifestations into a syndrome with the acronym SAPHO: synovitis, acne, pustulosis, hyperostosis, and osteitis (Chamot et al., 1987). Furthermore, the clinical feature of aseptic chronic recurrent multiple osteomyelitis (CRMO) accompanied by pustulosis with its typical presentation i...