The subjective and motor phenomena of neuroleptic-induced akathisia were studied in two different populations of psychiatric patients. Thirty nine (41%) of 95 patients attending community psychiatric centres and psychiatric day hospitals experienced a compulsion to move about, and 52 (55%) complained of restlessness of the body. Of 842 psychiatric in-patients 159 found to have marked hyperkines...

For a number of years, clinicians and researchers have recognized the existence of a subgrouping of children who exhibit chronic and pervasive signs of inattention, impulsivity, and physical restlessness, as well as deficiencies in rule-governed behavior, which deviate significantly from age and gender expectations (Barkley; 1981; Ross & Ross, 1982; Wender, 1971). Since first being identified b...

apical ballooning syndrome (abs) is a reversible cardiomyopathy with presentation mimicking an acute coronary syndrome. so in clinical practice, it is essential to consider it in the differential diagnosis of patients presenting with chest pain, especially in postmenopausal women. coronary angiography is usually indicated to achieve a proper diagnosis. typically, patients do not have significan...

This study aimed at determining the thermoregulatory phenotype of mice lacking transient receptor potential vanilloid-1 (TRPV1) channels. We used Trpv1 knockout (KO) mice and their genetically unaltered littermates to study diurnal variations in deep body temperature (T(b)) and thermoeffector activities under basal conditions, as well as thermoregulatory responses to severe heat and cold. Only ...

Introduction and Purpose Though the term folie Ii deux (Lasegue and Falret, 1877; Gralnick, 1942) is not common in current psychiatric usage, the phenomenon is recognized from time to time. In its strictest sense it means that two people manifest identically the same symptom, often an idee fixe, or a shared delusion. There is no literature on folie Ii deux in connection with the syndrome of rev...

Glutaric aciduria type 1 (glutaryl-CoA dehydrogenase deficiency, glutaric acidemia 1) (OMIM 231670) is an autosomal recessive disease caused by mutations in the gene encoding enzyme glutaryl-CoA (GCDH). Glutaryl-CoA (GCDH) plays important role degradation metabolism of L-lysine, L-hydroxylysine and L-tryptophan. The insufficiency or absence leads to accumulation by-products such amino acids as ...

The present study compared the efficacy of ACTH 4-9 analog, methylphenidate, and placebo on attention deficit disorder with 30 (HK) children with attention deficit disorder and psychometric measurements. HK children were randomly placed into three groups, according to body weight, and treated with placebo, methylphenidate, and adrenocorticotropic hormone fractions (ACTH 4-9 analog). The results...